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Shared Motivational Functions of Ventral Striatum D1 and D2 Medium Spiny Neurons.

作者信息

Flanigan Meghan, LeClair Katherine

机构信息

Graduate School of Biomedical Sciences and

Fishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029.

出版信息

J Neurosci. 2017 Jun 28;37(26):6177-6179. doi: 10.1523/JNEUROSCI.0882-17.2017.

DOI:10.1523/JNEUROSCI.0882-17.2017
PMID:28659329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5490058/
Abstract
摘要

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本文引用的文献

1
Ventrolateral Striatal Medium Spiny Neurons Positively Regulate Food-Incentive, Goal-Directed Behavior Independently of D1 and D2 Selectivity.腹外侧纹状体中等棘状神经元独立于D1和D2选择性，正向调节食物激励的目标导向行为。
J Neurosci. 2017 Mar 8;37(10):2723-2733. doi: 10.1523/JNEUROSCI.3377-16.2017. Epub 2017 Feb 6.
2
Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation.腹侧纹状体多巴胺受体 2 型表达的中型多棘神经元功能障碍会损害工具性动机。
Nat Commun. 2017 Feb 1;8:14304. doi: 10.1038/ncomms14304.
3
Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation.伏隔核中表达 D2 多巴胺受体的神经元的激活增加了动机。
Nat Commun. 2016 Jun 23;7:11829. doi: 10.1038/ncomms11829.
4
In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward.体内成像确定了可卡因奖赏中D1和D2中型棘状神经元的时间特征。
Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2726-31. doi: 10.1073/pnas.1521238113. Epub 2016 Feb 1.
5
Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections.通过D1和D2受体对直接/间接通路进行编码，对伏隔核投射而言是无效的。
Nat Neurosci. 2015 Sep;18(9):1230-2. doi: 10.1038/nn.4068. Epub 2015 Jul 27.
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Control of basal ganglia output by direct and indirect pathway projection neurons.直接和间接通路投射神经元对基底神经节输出的控制。
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Distinct roles for direct and indirect pathway striatal neurons in reinforcement.纹状体直接和间接通路神经元在强化中的不同作用。
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Science. 2010 Oct 15;330(6002):385-90. doi: 10.1126/science.1188472.
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Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry.通过光遗传学控制基底神经节回路调节帕金森运动行为。
Nature. 2010 Jul 29;466(7306):622-6. doi: 10.1038/nature09159. Epub 2010 Jul 7.