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肾移植患者播散性暗南尼兹菌感染——首例报告病例

Disseminated Nannizziopsis obscura infection in a renal transplant patient- The first reported case.

作者信息

Baggott Amy, McGann Hugh, Barton Richard, Ratner Jennifer

机构信息

Leeds Teaching Hospitals Trust, Department of Infection and Travel Medicine, St. James University Hospital, Beckett Street, Leeds LS9 7TF, United Kingdom.

Leeds Teaching Hospitals Trust, Mycology Reference Centre, Department of Microbiology, Old Medical School, Leeds General Infirmary, Leeds LS1 3EX, United Kingdom.

出版信息

Med Mycol Case Rep. 2017 Jun 9;17:20-24. doi: 10.1016/j.mmcr.2017.06.002. eCollection 2017 Sep.

DOI:10.1016/j.mmcr.2017.06.002
PMID:28664030
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5479955/
Abstract

This is a presentation of a case of disseminated fungal infection in a renal transplant patient with Nannizziopsis obscura, a species not previously reported as having caused disseminated disease in humans and not previously reported in the UK. The fungus was isolated from a intramuscular collection and from a lymph node. The patient responded well to a course of posaconazole.

摘要

本文介绍了一例肾移植患者发生播散性真菌感染的病例，病原体为隐匿南尼兹菌，该菌种此前未被报道可导致人类播散性疾病，在英国也未曾有过相关报道。该真菌从肌肉组织样本和淋巴结中分离得到。患者接受泊沙康唑治疗疗程后反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/61412b28d05b/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/a53440424c1f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/5962c5110933/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/8bee1767f7c0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/b21b8b776663/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/6402a3dda3c7/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/bfe54f536acf/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/e3123244b4b3/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/fb3836e73993/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/61412b28d05b/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/a53440424c1f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/5962c5110933/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/8bee1767f7c0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/b21b8b776663/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/6402a3dda3c7/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/bfe54f536acf/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/e3123244b4b3/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/fb3836e73993/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6167/5479955/61412b28d05b/gr9.jpg

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引用本文的文献

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Breast abscess due to Nannizziopsis obscura in an immunocompromised renal transplant patient after travel to Nigeria: case report and review.免疫功能低下的肾移植患者前往尼日利亚旅行后因 Nannizziopsis obscura 引起的乳腺脓肿：病例报告及文献复习。
BMC Infect Dis. 2023 Jan 24;23(1):50. doi: 10.1186/s12879-022-07958-3.
2
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Emerg Infect Dis. 2022 Sep;28(9):1929-1931. doi: 10.3201/eid2809.220375.
3
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本文引用的文献

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Persoonia. 2013 Dec;31:86-100. doi: 10.3767/003158513X669698. Epub 2013 Jun 17.
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Chrysosporium anamorph Nannizziopsis vriesii: an emerging fungal pathogen of captive and wild reptiles.金孢子菌无性型弗氏南尼兹菌：一种圈养和野生爬行动物新出现的真菌病原体。
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Molecular characterization of reptile pathogens currently known as members of the chrysosporium anamorph of Nannizziopsis vriesii complex and relationship with some human-associated isolates.
一名艾滋病患者的免疫重建炎症综合征：首例报告病例
Eur J Case Rep Intern Med. 2021 Nov 23;8(11):003021. doi: 10.12890/2021_003021. eCollection 2021.
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Cross-continental emergence of Nannizziopsis barbatae disease may threaten wild Australian lizards.巴塔叶瘿蚊病在跨大陆的出现可能威胁到澳大利亚野生蜥蜴。
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Disseminated Infection in an Adolescent With a Mutation.一名患有突变的青少年的播散性感染
Open Forum Infect Dis. 2020 Aug 27;7(9):ofaa390. doi: 10.1093/ofid/ofaa390. eCollection 2020 Sep.
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Invasive Infections with Nannizziopsis obscura Species Complex in 9 Patients from West Africa, France, 2004-2020.2004-2020 年，来自西非、法国的 9 名患者感染 Nannizziopsis obscura 种复合体所致侵袭性感染。
Emerg Infect Dis. 2020 Sep;26(9):2022-30. doi: 10.3201/eid2609.200276.
目前已知属于 Nannizziopsis vriesii 复合种 Chrysosporium 无性型成员的爬行动物病原体的分子特征及其与一些与人类相关的分离物的关系。
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Dermatitis and cellulitis in leopard geckos (Eublepharis macularius) caused by the Chrysosporium anamorph of Nannizziopsis vriesii.由弗里西拟南芥金孢子菌无性型引起的豹纹守宫（睑虎）皮炎和蜂窝织炎
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Deep fungal dermatitis in three inland bearded dragons (Pogona vitticeps) caused by the Chrysosporium anamorph of Nannizziopsis vriesii.三只内陆鬃狮蜥（鬃狮蜥）发生由弗里西拟南芥金孢子菌无性型引起的深部真菌性皮炎。
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