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金孢子菌无性型弗氏南尼兹菌:一种圈养和野生爬行动物新出现的真菌病原体。

Chrysosporium anamorph Nannizziopsis vriesii: an emerging fungal pathogen of captive and wild reptiles.

作者信息

Mitchell Mark A, Walden Michael R

机构信息

Department of Veterinary Clinical Medicine, University of Illinois, College of Veterinary Medicine, 1008 West Hazelwood Drive, Urbana, IL 61802, USA.

出版信息

Vet Clin North Am Exot Anim Pract. 2013 Sep;16(3):659-68. doi: 10.1016/j.cvex.2013.05.013. Epub 2013 Jul 17.

DOI:10.1016/j.cvex.2013.05.013
PMID:24018030
Abstract

Chrysosporium anamorph Nannizziopsis vriesii is a recent pathogen associated with infections in lizards, snakes, and crocodilians. It seems to be an obligate pathogen. It has been isolated from wild reptiles in addition to captive animals. Affected animals often present with aggressive, pyogranulomatous lesions that can affect the integument and musculoskeletal systems. Diagnosis can be done using culture, histopathology, and polymerase chain reaction assay. Ancillary diagnostic tests can be useful in characterizing the health status of the affected reptile and aid in planning supportive care and therapy. Treatment using antifungals has shown mixed results.

摘要

变形金孢霉(无性型为弗里西拟南芥霉)是一种最近发现的与蜥蜴、蛇和鳄鱼感染相关的病原体。它似乎是一种专性病原体。除了圈养动物外,它还从野生爬行动物中分离出来。受感染的动物通常会出现侵袭性的脓性肉芽肿病变,可影响皮肤和肌肉骨骼系统。诊断可通过培养、组织病理学和聚合酶链反应检测来进行。辅助诊断测试有助于确定受感染爬行动物的健康状况,并有助于规划支持性护理和治疗。使用抗真菌药物治疗的结果不一。

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