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[肌肉骨骼因素、肌肉减少症与老年人跌倒]

[Musculoskeletal factors, sarcopenia and falls in old age].

作者信息

Schoene Daniel, Kiesswetter Eva, Sieber Cornel C, Freiberger Ellen

机构信息

Institut für Biomedizin des Alterns, Friedrich-Alexander-Universität Erlangen-Nürnberg, Kobergerstr. 60, 90408, Nürnberg, Deutschland.

Klinik für Allgemeine Innere Medizin und Geriatrie, Krankenhaus Barmherzige Brüder, Regensburg, Deutschland.

出版信息

Z Gerontol Geriatr. 2019 Feb;52(1):37-44. doi: 10.1007/s00391-017-1283-6. Epub 2017 Jun 29.

DOI:10.1007/s00391-017-1283-6
PMID:28664287
Abstract

Falls in older adults are a major public health problem with a high incidence and severe consequences for the older individual. The age-related loss of muscle strength as well as muscle mass and muscle function (sarcopenia) are i) risk factors for falling, ii) associated with physical function and iii) markers of the frailty syndrome. Muscle function appears to play a bigger role than muscle mass. The operationalization of sarcopenia using the European Working Group on Sarcopenia in Older People (EWGSOP) algorithm is consistently associated with falling events. Structured physical exercise plays the key role in the prevention of falls and the management of functional decline caused by sarcopenia and frailty. The combined supplementation with proteins and vitamin D supports muscle protein synthesis in undersupplied persons and improves aspects of physical function.

摘要

老年人跌倒问题是一个重大的公共卫生问题,发生率高,对老年人个体造成严重后果。与年龄相关的肌肉力量、肌肉质量和肌肉功能丧失(肌少症):一是跌倒的风险因素;二是与身体功能相关;三是衰弱综合征的标志物。肌肉功能似乎比肌肉质量发挥着更大的作用。使用欧洲老年人肌少症工作组(EWGSOP)算法对肌少症进行操作化定义,始终与跌倒事件相关。有组织的体育锻炼在预防跌倒以及管理由肌少症和衰弱引起的功能衰退方面起着关键作用。蛋白质和维生素D联合补充剂可支持蛋白质供应不足人群的肌肉蛋白质合成,并改善身体功能的各个方面。

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Exercise to prevent falls in older adults: an updated systematic review and meta-analysis.老年人跌倒预防的运动干预:一项更新的系统评价和荟萃分析。
Br J Sports Med. 2017 Dec;51(24):1750-1758. doi: 10.1136/bjsports-2016-096547. Epub 2016 Oct 4.
2
Strength measures are better than muscle mass measures in predicting health-related outcomes in older people: time to abandon the term sarcopenia?在预测老年人与健康相关的结果方面,力量测量比肌肉量测量更具优势:是时候摒弃“肌肉减少症”这个术语了吗?
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High risk of fall, poor physical function, and low grip strength in men with fracture-the STRAMBO study.
老年人行走速度与年龄相关下降的决定因素。
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Int J Environ Res Public Health. 2022 Aug 30;19(17):10789. doi: 10.3390/ijerph191710789.
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Prevalence of Sarcopenia in Older South African Patients Following Surgery for Fragility Fractures of the Hip.南非老年患者髋部脆性骨折手术后肌肉减少症的患病率
Geriatr Orthop Surg Rehabil. 2020 Nov 26;11:2151459320971560. doi: 10.1177/2151459320971560. eCollection 2020.
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Preserved Capacity for Adaptations in Strength and Muscle Regulatory Factors in Elderly in Response to Resistance Exercise Training and Deconditioning.老年人对阻力运动训练和去适应状态做出反应时,其力量和肌肉调节因子的适应能力得以保留。
J Clin Med. 2020 Jul 10;9(7):2188. doi: 10.3390/jcm9072188.
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[Becoming older with axial spondyloarthritis].[随着年龄增长的轴性脊柱关节炎]
Z Rheumatol. 2018 Jun;77(5):363-368. doi: 10.1007/s00393-018-0446-1.
骨折男性跌倒风险高、身体功能差及握力低——STRAMBO研究
J Cachexia Sarcopenia Muscle. 2016 Jun;7(3):299-311. doi: 10.1002/jcsm.12066. Epub 2015 Nov 19.
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Br J Sports Med. 2017 Apr;51(7):586-593. doi: 10.1136/bjsports-2015-095452. Epub 2016 Jan 8.
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