Poikayil Rona Joseph, Narayanan Geetha, Sugathan Harish, Soman Lali V
Department of Medical Oncology, Regional Cancer Centre, Trivandrum, India.
Proc (Bayl Univ Med Cent). 2017 Jul;30(3):334-335. doi: 10.1080/08998280.2017.11929638.
Leukemia cutis and neuroleukemiosis are two rare extramedullary manifestations of acute leukemia. We report a 32-year-old woman with multiple skin lesions and painful peripheral neuropathy. Bone marrow biopsy and skin biopsy confirmed the diagnosis of mixed phenotypic acute leukemia. After induction chemotherapy, she attained marrow remission, her skin lesion resolved completely, and her neurologic symptoms significantly improved.
皮肤白血病和神经白血病是急性白血病两种罕见的髓外表现。我们报告一名32岁女性,有多处皮肤病变和疼痛性周围神经病变。骨髓活检和皮肤活检确诊为混合表型急性白血病。诱导化疗后,她达到骨髓缓解,皮肤病变完全消退,神经症状明显改善。