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芬兰全国疫苗接种计划对地方性麻疹、腮腺炎和风疹的快速影响。

Rapid effect on endemic measles, mumps, and rubella of nationwide vaccination programme in Finland.

作者信息

Peltola H, Karanko V, Kurki T, Hukkanen V, Virtanen M, Penttinen K, Nissinen M, Heinonen O P

出版信息

Lancet. 1986 Jan 18;1(8473):137-9. doi: 10.1016/s0140-6736(86)92270-1.

Abstract

An immunisation programme to eliminate measles, mumps, and rubella from Finland within 10 years was started in November, 1982. A combined live vaccine is being given twice, at the ages of 14-18 months and 6 years, but at the beginning of the project children between these age limits are also being immunised. Because vaccinations are traditionally done by the public health nurses, special attention was paid to their motivation. 2.5 years after the launch of the project, 80.9% of the target children had been vaccinated. The incidence of measles has fallen by 93% and that of mumps by 87% compared with a normal prevaccination year (1982). A similar fall in incidence was seen for rubella, but only in the vaccinated age groups. Although elimination of measles, mumps, and rubella is not likely to be achieved with the present vaccination coverage, a drastic fall in the incidence of all three target diseases has occurred already. Every effort is being made to improve the coverage and thus to achieve the ultimate goal of the project.

摘要

1982年11月,芬兰启动了一项在10年内消除麻疹、腮腺炎和风疹的免疫计划。一种联合活疫苗分两次接种,分别在14至18个月和6岁时接种,但在项目开始时,处于这些年龄限制之间的儿童也在接受免疫接种。由于传统上疫苗接种由公共卫生护士进行,因此特别关注了他们的积极性。项目启动2.5年后,80.9%的目标儿童已接种疫苗。与疫苗接种前的正常年份(1982年)相比,麻疹发病率下降了93%,腮腺炎发病率下降了87%。风疹发病率也出现了类似的下降,但仅在接种疫苗的年龄组中。尽管以目前的疫苗接种覆盖率不太可能实现消除麻疹、腮腺炎和风疹的目标,但这三种目标疾病的发病率已经大幅下降。正在尽一切努力提高覆盖率,从而实现该项目的最终目标。

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