Haine Aung Thu, Niidome Takuro
Department of Advanced Science and Technology, Kumamoto University.
Department of Chemical Engineering, Yangon Technological University.
Chem Pharm Bull (Tokyo). 2017;65(7):625-628. doi: 10.1248/cpb.c17-00102.
Gold nanorods are promising metals in several biomedical applications such as bioimaging, thermal therapy, and drug delivery. Gold nanorods have strong absorption bands in near-infrared (NIR) light region and show photothermal effects. Since NIR light can penetrate deeply into tissues, their unique optical, chemical, and biological properties have attracted considerable clinical interest. Gold nanorods are expected to act not only as on-demand thermal converters for photothermal therapy but also as mediators of a controlled drug-release system responding to light irradiation. In this review, we discuss current progress using gold nanorods as bioimaging platform, phototherapeutic agents, and drug delivery vehicles.
金纳米棒在生物成像、热疗和药物递送等多种生物医学应用中是很有前景的金属。金纳米棒在近红外（NIR）光区域有很强的吸收带，并表现出光热效应。由于近红外光可以深入穿透组织，其独特的光学、化学和生物学特性引起了临床的广泛关注。金纳米棒不仅有望作为光热疗法的按需热转换器，还能作为响应光照射的可控药物释放系统的介质。在这篇综述中，我们讨论了使用金纳米棒作为生物成像平台、光治疗剂和药物递送载体的当前进展。
