Vaccine and Gene Therapy Institute at Oregon Health and Science University, Beaverton, OR, USA.
Curr Top Microbiol Immunol. 2018;419:243-280. doi: 10.1007/82_2017_31.
Non-coding RNAs (ncRNAs) play essential roles in multiple aspects of the life cycles of herpesviruses and contribute to lifelong persistence of herpesviruses within their respective hosts. In this chapter, we discuss the types of ncRNAs produced by the different herpesvirus families during infection, some of the cellular ncRNAs manipulated by these viruses, and the overall contributions of ncRNAs to the viral life cycle, influence on the host environment, and pathogenesis.
非编码 RNA（ncRNA）在疱疹病毒的生命周期的多个方面发挥着重要作用，并有助于疱疹病毒在其各自宿主中终生持续存在。在本章中，我们讨论了不同疱疹病毒家族在感染过程中产生的 ncRNA 类型、这些病毒操纵的一些细胞 ncRNA，以及 ncRNA 对病毒生命周期、宿主环境和发病机制的整体影响。
