Kumar Pradeep, Ravani Raghav, Kakkar Prateek, Sharma Anu, Kumar Atul
Unit 2, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Int Ophthalmol. 2018 Aug;38(4):1769-1773. doi: 10.1007/s10792-017-0624-1. Epub 2017 Jul 4.
To report the first case report of an association between flupentixol and crystalline retinopathy.
Observational, Case report.
We report a case of crystalline retinopathy in a 36-year-old female who was suffering from depression and being treated with tablet flupentixol in a cumulative dose of 4380 mg over two years. Fundus examination of both eyes showed multiple, discrete, yellowish white refractile intraretinal deposits over the macula and peripapillary region, located in the inner retina as shown by OCT.
We propose regular retinal evaluation in patients with chronic flupentixol intake and larger studies to establish causal relationship between flupentixol and crystalline retinopathy.