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Ultrastructural features of ethanol-induced cardiomyopathy in turkey poults.

作者信息

Czarnecki C M, Schaffer S W, Evanson O A

出版信息

Comp Biochem Physiol A Comp Physiol. 1985;82(4):939-43. doi: 10.1016/0300-9629(85)90509-2.

DOI:10.1016/0300-9629(85)90509-2
PMID:2867855
Abstract

Alcoholic cardiomyopathy, characterized by cardiac hypertrophy, was induced in young turkey poults with 5% ethanol. Ultrastructural features included accumulation of glycogen, swollen mitochondria, myofibrillar lysis, increased number of lysosomes, dilated sarcoplasmic reticulum and dense myofibers. Similarity of these alterations to those described in human alcoholic cardiomyopathy confirms the usefulness of the turkey poult as an animal model for this disease syndrome.

摘要

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