Zherdev V P, Aleksandrovskiĭ Iu A, Neznamov G G, Rudenko G M, Antokhin E A
Farmakol Toksikol. 1987 Jan-Feb;50(1):81-5.
A high degree of correlation between experimentally established and theoretically calculated constant concentrations of phenazepam was revealed in blood plasma of patients. Due to experimental findings the employment of a single-dose drug administration with regard to previously stated effective-dose interval during dosage build-up made possible estimating the maximum allowable individual dosage which should yield a good therapeutic result without side effects.
在患者血浆中发现，实验确定的和理论计算的芬那西泮恒定浓度之间存在高度相关性。基于实验结果，在剂量递增过程中，按照先前所述的有效剂量间隔采用单剂量给药，使得估算最大允许个体剂量成为可能，该剂量应能产生良好的治疗效果且无副作用。
