Boix R, Cano R, Gallego P, Vallejo F, Fernández-Cuenca R, Noguer I, Larrauri A
National Centre of Epidemiology, Institute of Health Carlos III, C/Monforte de Lemos, 5, 28029, Madrid, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), C/ Monforte de Lemos, 3-5, 28029, Madrid, Spain.
BMC Health Serv Res. 2017 Jul 5;17(1):461. doi: 10.1186/s12913-017-2410-1.
Hepatitis C is an important public health problem about which there is currently scarce epidemiological information. The objective of this study is to describe and analyse the demographic and epidemiological characteristics of hospitalized cases of hepatitis C in the Spanish population between 2004 and 2013.
The study uses the Hospital Discharge Records Database of the Spanish National Health System. It is a retrospective descriptive epidemiological study. The variables analysed were year of infection, age, sex, diagnostic category, days admitted and co-morbidity.
There have been a total of 351,996 hospitalizations; 225,138 men (64%) and 126,858 women (36%). They are divided between acute hepatitis 8161 (2.3%); chronic hepatitis 325,185 (92.4%) and unspecified hepatitis 18,650 (5.3%). The mean age for men is 53.7 (+/-15.2) and for women 62.3 (+/-17.3). 22.8% also present with an Human immunodeficiency virus (HIV) disease coinfection, and 14.7% with opioid dependencies. The trend is for a gradual increase in cases without statistical significance.
The Hepatitis C cases hospitalized had high levels of chronicity, which entails two distinct patterns of illness in men and women - who are affected in different age ranges.
丙型肝炎是一个重要的公共卫生问题，目前关于它的流行病学信息匮乏。本研究的目的是描述和分析2004年至2013年西班牙人群中丙型肝炎住院病例的人口统计学和流行病学特征。
本研究使用西班牙国家卫生系统的医院出院记录数据库。这是一项回顾性描述性流行病学研究。分析的变量包括感染年份、年龄、性别、诊断类别、住院天数和合并症。
共有351,996例住院病例；男性225,138例（64%），女性126,858例（36%）。其中急性肝炎8161例（2.3%）；慢性肝炎325,185例（92.4%），未明确的肝炎18,650例（5.3%）。男性的平均年龄为53.7岁（±15.2），女性为62.3岁（±17.3）。22.8%的病例还合并人类免疫缺陷病毒（HIV）感染，14.7%的病例有阿片类药物依赖。病例数呈逐渐增加趋势，但无统计学意义。
丙型肝炎住院病例的慢性化程度较高，这在男性和女性中呈现出两种不同的疾病模式——他们在不同年龄范围内受到影响。
