Hull R, Bieler S, Falkow S, Hull S
Infect Immun. 1986 Feb;51(2):693-5. doi: 10.1128/iai.51.2.693-695.1986.
Escherichia coli isolates from upper urinary tract infections frequently express adherence to human uroepithelium and D-mannose-resistant hemagglutination of human erythrocytes. Such adherence is usually associated with P pili encoded by the pap operon(s). In this paper, we report approximate chromosomal map positions for two copies of the pap operon. Only one copy expressed an adhesin capable of D-mannose-resistant hemagglutination, although both expressed P-related antigen.
从上行性尿路感染中分离出的大肠杆菌菌株常常表现出对人尿道上皮的黏附以及对人红细胞的D-甘露糖抗性血凝作用。这种黏附通常与由pap操纵子编码的P菌毛有关。在本文中,我们报告了pap操纵子两个拷贝的大致染色体图谱位置。尽管两个拷贝都表达与P相关的抗原,但只有一个拷贝表达能够产生D-甘露糖抗性血凝作用的黏附素。