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Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.

作者信息

Iadarola M J, Shin C, McNamara J O, Yang H Y

出版信息

Brain Res. 1986 Feb 12;365(1):185-91. doi: 10.1016/0006-8993(86)90738-9.

DOI:10.1016/0006-8993(86)90738-9
PMID:2868784
Abstract

Amygdaloid kindling of rats produced an increase in hippocampal Met5-enkephalin-Arg6-Gly7-Leu8 and cholecystokinin immunoreactivities and simultaneously a decrease in dynorphin A1-8 content. In substantia nigra Met5-enkephalin-Arg6-Gly7-Leu8 was increased and no change was observed in dynorphin A1-8 content. These data suggest that specific alterations of neuropeptides in limbic and extrapyramidal circuits are prominent manifestations of the kindling process or kindled seizures.

摘要

相似文献

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