Shome Rajeswari, Kalleshamurthy Triveni, Shankaranarayana Padmashree B, Giribattanvar Prashanth, Chandrashekar Nagarathna, Mohandoss Nagalingam, Shome Bibek Ranjan, Kumar Ashok, Barbuddhe Sukhadeo B, Rahman Habibur
a ICAR-National Institute of Veterinary Epidemiology and Disease Informatics , Bengaluru , India.
b Department of Neuromicrobiology , National Institute of Mental Health and Neuro Sciences , Bengaluru , India.
Pathog Glob Health. 2017 Jul;111(5):234-239. doi: 10.1080/20477724.2017.1345366. Epub 2017 Jul 8.
The study describes prevalence, clinical symptoms and risk factors for brucellosis in personnel engaged in veterinary health care in Karnataka, India. A total of 1050 sera samples were collected from animal handlers, veterinarians, veterinary students, para-veterinarians and persons engaged in artificial insemination of animals. The sera samples were tested for brucellosis by Rose Bengal plate test (RBPT), serum agglutination test (SAT), IgG and IgM indirect ELISA and PCR. Age, sex, clinical symptoms and risk factors were recorded in structured questionnaire. Of the 1050 samples tested, 6.76, 6.38, 3.90, 2.67 and 2.0% were positive by IgG ELISA, RBPT, SAT, IgM ELISA and PCR, respectively and overall prevalence recorded was 7.04%. The prominent clinical symptoms observed were intermittent fever (71.62%) followed by joint pain and body aches. A high degree of suspicion, awareness and multimodal diagnostic approach is suggested for early diagnosis, treatment and disease follow up.
该研究描述了印度卡纳塔克邦从事兽医保健工作的人员中布鲁氏菌病的患病率、临床症状和危险因素。总共从动物饲养员、兽医、兽医学生、准兽医和从事动物人工授精的人员中收集了1050份血清样本。通过玫瑰红平板试验（RBPT）、血清凝集试验（SAT）、IgG和IgM间接酶联免疫吸附测定（ELISA）以及聚合酶链反应（PCR）对血清样本进行布鲁氏菌病检测。通过结构化问卷记录年龄、性别、临床症状和危险因素。在检测的1050份样本中，IgG ELISA、RBPT、SAT、IgM ELISA和PCR的阳性率分别为6.76%、6.38%、3.90%、2.67%和2.0%，总体患病率为7.04%。观察到的主要临床症状为间歇性发热（71.62%），其次是关节疼痛和身体疼痛。建议高度怀疑、提高认识并采用多模式诊断方法进行早期诊断、治疗和疾病随访。
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