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脊髓损伤患者神经源性肠道功能障碍评分的可靠性、有效性及对变化的敏感性

Reliability, validity and sensitivity to change of neurogenic bowel dysfunction score in patients with spinal cord injury.

作者信息

Erdem D, Hava D, Keskinoğlu P, Bircan Ç, Peker Ö, Krogh K, Gülbahar S

机构信息

Department of Physical Medicine and Rehabilitation, Dokuz Eylül University, Faculty of Medicine, Izmir, Turkey.

Department of Biostatics and Medical Informatics, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.

出版信息

Spinal Cord. 2017 Dec;55(12):1084-1087. doi: 10.1038/sc.2017.82. Epub 2017 Jul 11.

DOI:10.1038/sc.2017.82
PMID:28695900
Abstract

STUDY DESIGN

Psychometrics study.

OBJECTIVES

The aim of this study is to investigate the validity, reliability and sensitivity to change of neurogenic bowel dysfunction (NBD) score.

SETTING

Dokuz Eylül University Faculty of Medicine, Turkey.

METHODS

The study included 42 patients with spinal cord injury (SCI). The reliability of NBD score was assessed by test-retest reliability and internal consistency. Cronbach's alpha coefficient was calculated to determine internal consistency. The construct validity was evaluated by exploring correlations between the NBD score and SF-36 scales, patient assessment of impact of NBD on quality of life (QoL) and the physician global assessment (PGA). The Global Rating of Change (GRC) scale was used to assess the change of NBD to investigate the sensitivity of the score to change.

RESULTS

Cronbach's alpha coefficient was 0.547. In test-retest reliability analysis, high correlations between total test-retest NBD score and answers of each question were found (r=1.000, P<0.001). NBD score had a strong and significant correlation with PGA (r=0.98, P<0.000) and the impact on QoL (r=0.92, P<0.001). There was a significant negative correlation between NBD score and subscales of SF-36 (P<0.05) except physical functioning, physical role functioning and physical component summary score. There was a significant improvement in NBD scores after treatment (P=0.011). A significant positive correlation was found between GRC scale and change in total NBD score (r=0.821, P=0.007).

CONCLUSION

The Turkish version of the NBD score is a valid and reliable instrument and also sensitive to change in patients with SCI.

摘要

研究设计

心理测量学研究。

目的

本研究旨在调查神经源性肠道功能障碍(NBD)评分的效度、信度及对变化的敏感性。

地点

土耳其多库兹艾吕尔大学医学院。

方法

该研究纳入了42例脊髓损伤(SCI)患者。通过重测信度和内部一致性评估NBD评分的信度。计算克朗巴赫α系数以确定内部一致性。通过探究NBD评分与SF-36量表、患者对NBD对生活质量(QoL)影响的评估以及医生整体评估(PGA)之间的相关性来评估结构效度。使用总体变化评分(GRC)量表评估NBD的变化,以研究该评分对变化的敏感性。

结果

克朗巴赫α系数为0.547。在重测信度分析中,发现重测NBD总分与每个问题的答案之间存在高度相关性(r = 1.000,P < 0.001)。NBD评分与PGA(r = 0.98,P < 0.000)以及对QoL的影响(r = 0.92,P < 0.001)具有强且显著的相关性。除身体功能、身体角色功能和身体成分汇总评分外,NBD评分与SF-36的子量表之间存在显著负相关(P < 0.05)。治疗后NBD评分有显著改善(P = 0.011)。GRC量表与NBD总分变化之间存在显著正相关(r = 0.821,P = 0.007)。

结论

土耳其版NBD评分是一种有效且可靠的工具,对SCI患者的变化也具有敏感性。

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