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前葡萄膜炎的多模态成像

Multimodal Imaging in Anterior Uveitis.

作者信息

Siak Jay, Mahendradas Padmamalini, Chee Soon-Phaik

机构信息

a Ocular Inflammation and Immunology Service , Singapore National Eye Centre , Singapore.

b Ocular Inflammation and Immunology Research Group, Singapore Eye Research Institute , Singapore.

出版信息

Ocul Immunol Inflamm. 2017 Jun;25(3):434-446. doi: 10.1080/09273948.2017.1327601.

DOI:10.1080/09273948.2017.1327601
PMID:28696173
Abstract

Anterior uveitis is the most common group of uveitis worldwide, with a diverse spectrum ranging from autoimmune and infectious to masquerade etiologies. Elucidation of the underlying etiology may be challenging, but it remains important, especially for recurrent uveitis. Multimodal imaging has improved our understanding and management of many posterior uveitis and panuveitis. Similarly, a wide variety of anterior segment ophthalmic imaging techniques are available to allow the monitoring of the structural changes that may develop during anterior uveitis. These include anterior segment photography, specular microscopy, in vivo confocal microscopy, anterior segment optical coherence tomography (AS-OCT), ultrasound biomicroscopy (UBM), laser flare photometry, and less commonly used techniques such as anterior segment fluorescein and indocyanine green angiography, iris autofluorescence, and infrared imaging. This review recapitulates the past and recent application of these ophthalmic imaging modalities to the diagnosis and management of anterior uveitis.

摘要

前葡萄膜炎是全球最常见的葡萄膜炎类型,病因多样,涵盖自身免疫性、感染性及伪装综合征等。明确潜在病因可能具有挑战性,但仍然很重要,特别是对于复发性葡萄膜炎。多模态成像改善了我们对许多后葡萄膜炎和全葡萄膜炎的理解与管理。同样,有多种眼前段眼科成像技术可用于监测前葡萄膜炎期间可能出现的结构变化。这些技术包括眼前段摄影、镜面显微镜检查、活体共聚焦显微镜检查、眼前段光学相干断层扫描(AS-OCT)、超声生物显微镜检查(UBM)、激光 flare 光度测定法,以及较少使用的技术,如眼前段荧光素和吲哚菁绿血管造影、虹膜自发荧光和红外成像。本综述概述了这些眼科成像方式在诊断和管理前葡萄膜炎方面的过去和近期应用。

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