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使用极低能量脉冲激光二极管开发低成本光声成像系统。

Development of low-cost photoacoustic imaging systems using very low-energy pulsed laser diodes.

机构信息

Wayne State University, Bioengineering Department, Detroit, Michigan, United StatesbUniversity of California, Department of NanoEngineering, San Diego, California, United States.

Wayne State University, Bioengineering Department, Detroit, Michigan, United States.

出版信息

J Biomed Opt. 2017 Jul 1;22(7):75001. doi: 10.1117/1.JBO.22.7.075001.

Abstract

With the growing application of photoacoustic imaging (PAI) in medical fields, there is a need to make them more compact, portable, and affordable. Therefore, we designed very low-cost PAI systems by replacing the expensive and sophisticated laser with a very low-energy laser diode. We implemented photoacoustic (PA) microscopy, both reflection and transmission modes, as well as PA computed tomography systems. The images obtained from tissue-mimicking phantoms and biological samples determine the feasibility of using a very low-energy laser diode in these configurations.

摘要

随着光声成像(PAI)在医学领域的应用日益广泛,人们需要使这些系统更加紧凑、便携和经济实惠。因此,我们通过用低能量激光二极管代替昂贵而复杂的激光器来设计非常低成本的 PAI 系统。我们实现了光声(PA)显微镜,包括反射和透射模式,以及 PA 计算机断层扫描系统。从组织模拟体模和生物样本中获得的图像确定了在这些配置中使用低能量激光二极管的可行性。

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