Zeng Lvming, Liu Guodong, Yang Diwu, Ji Xuanrong
Key Laboratory of Optic-Electronic and Communication, Jiangxi Sciences and Technology Normal College, Nanchang, China.
Opt Express. 2012 Jan 16;20(2):1237-46. doi: 10.1364/OE.20.001237.
We present a 3D-visual laser-diode-based photoacoustic imaging (LD-PAI) system with a pulsed semiconductor laser source, which has the properties of being inexpensive, portable, and durable. The laser source was operated at a wavelength of 905 nm with a repetition rate of 0.8 KHz. The energy density on the sample surface is about 2.35 mJ/cm(2) with a pulse energy as low as 5.6 μJ. By raster-scanning, preliminary 3D volumetric renderings of the knotted and helical blood vessel phantoms have been visualized integrally with an axial resolution of 1.1 mm and a lateral resolution of 0.5 mm, and typical 2D photoacoustic image slices with different thickness and orientation were produced with clarity for detailed comparison and analysis in 3D diagnostic visualization. In addition, the pulsed laser source was integrated with the optical lens group and the 3D adjustable rotational stage, with the result that the compact volume of the total radiation source is only 10 × 3 × 3 cm(3). Our goal is to significantly reduce the costs and sizes of the deep 3D-visual PAI system for future producibility.
我们展示了一种基于三维视觉激光二极管的光声成像（LD-PAI）系统，该系统采用脉冲半导体激光源，具有价格低廉、便于携带和耐用的特点。激光源工作波长为905nm，重复频率为0.8kHz。样品表面的能量密度约为2.35mJ/cm²，脉冲能量低至5.6μJ。通过光栅扫描，对打结和螺旋状血管模型进行了初步的三维体积渲染，整体可视化效果良好，轴向分辨率为1.1mm，横向分辨率为0.5mm，并生成了具有不同厚度和方向的典型二维光声图像切片，清晰度高，便于在三维诊断可视化中进行详细比较和分析。此外，脉冲激光源与光学透镜组和三维可调旋转台集成在一起，整个辐射源的紧凑体积仅为10×3×3cm³。我们的目标是大幅降低用于未来生产的深度三维视觉PAI系统的成本和尺寸。
