Ghaffari Javad, Rokni Ghasem Rahmatpour, Kazeminejad Armaghan, Abedi Hosein
Infectious Disease Research Center with Focus on Nosocomial Infection, Bou-Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Mazandaran University of Medical Sciences, Sari, Iran.
Open Access Maced J Med Sci. 2017 Jun 11;5(3):305-309. doi: 10.3889/oamjms.2017.050. eCollection 2017 Jun 15.
Alopecia areata is a non-scarring hair loss, which typically starts quickly. Atopy is one of the possible predisposing risk factors for this condition.
This study aimed to evaluate the prevalence of thyroid disease, atopic dermatitis and allergic diseases in children with alopecia areata and compare the results with healthy individuals.
This case-control study was conducted on 50 patients with alopecia areata, diagnosed by a dermatologist, and 150 healthy individuals as the control group. Participants filled the questionnaires, and necessary tests were performed.
In this study, the mean age of the participants was 2.55 ± 14.26 and 3.19 ± 11.92 in the case and control groups, respectively. Prevalence of asthma was 22% in the case group and 12.5% in control group (P = 0.109). Also, allergic rhinitis and eczema were observed in 20% and 22% of the subjects of the case group, whereas they were reported to be 8% and 10% in the control group (PV = 0.03 and 0.175, respectively). Moreover, 28% and 8% of the participants in the case and control groups had a family history of atopy and allergic disorders, respectively (P = 0.046). A significant difference was observed between the two groups regarding gender, type of delivery and contact with animals.
According to the results of this study, a significant association was observed between the prevalence of alopecia areata and atopic conditions, such as allergic rhinitis and history of atopic dermatitis.
斑秃是一种非瘢痕性脱发，通常起病迅速。特应性是该疾病可能的诱发危险因素之一。
本研究旨在评估斑秃患儿甲状腺疾病、特应性皮炎和过敏性疾病的患病率，并将结果与健康个体进行比较。
本病例对照研究选取了50例经皮肤科医生诊断为斑秃的患者作为病例组，150名健康个体作为对照组。参与者填写问卷，并进行必要的检查。
本研究中，病例组和对照组参与者的平均年龄分别为2.55±14.26岁和3.19±11.92岁。病例组哮喘患病率为22%，对照组为12.5%（P = 0.109）。此外，病例组中20%和22%的受试者患有过敏性鼻炎和湿疹，而对照组报告的患病率分别为8%和10%（P值分别为0.03和0.175）。此外，病例组和对照组分别有28%和8%的参与者有特应性和过敏性疾病家族史（P = 0.046）。两组在性别、分娩方式和与动物接触方面存在显著差异。
根据本研究结果，观察到斑秃患病率与特应性疾病如过敏性鼻炎和特应性皮炎病史之间存在显著关联。
