School of Biological Science and Technology, University of Jinan, No. 336 West Road of Nanxinzhuang, Jinan 250022, Shandong Province, China.
School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, No.l6866 East Road of Jingshi, Jinan 250200, Shandong Province, PR China.
Anticancer Agents Med Chem. 2018 Feb 7;17(14):1884-1897. doi: 10.2174/1871520617666170713151149.
Liver cancer is one of serious diseases which threaten human life and health. Studies on the treatment of liver cancer have attracted widespread attention. Application of nano-drug delivery system (NDDS) can not only improve selective drug delivery to liver tissue and improve the bioavailability of drug, but also can reduce the side effects of drugs when it is specially modified in the respects of structure modification or specific target molecules decoration. This review will address the latest development of liver-targeted drug delivery system.
肝癌是严重威胁人类生命和健康的疾病之一。肝癌治疗的研究受到广泛关注。纳米药物递送系统（NDDS）的应用不仅可以提高药物对肝组织的选择性递送，提高药物的生物利用度，而且可以通过结构修饰或特定靶分子修饰等方面进行专门修饰，降低药物的副作用。本综述将介绍肝靶向药物递送系统的最新研究进展。
