大鼠新纹状体中脑啡肽能神经元多巴胺能输入的超微结构证据。
Ultrastructural evidence of dopaminergic input to enkephalinergic neurons in rat neostriatum.
作者信息
Kubota Y, Inagaki S, Kito S, Takagi H, Smith A D
出版信息
Brain Res. 1986 Mar 5;367(1-2):374-8. doi: 10.1016/0006-8993(86)91622-7.
The synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of ENK-immunoreactive (ENK-IR) neurons were very thin (0.1-0.4 micrograms). They contained many small clear vesicles and sometimes had symmetrical membrane specializations. This provides morphological evidence for catecholaminergic, presumably dopaminergic inputs to rat striatal enkephalin neurons.
采用“镜像技术”，在大鼠新纹状体相邻切片中研究了与酪氨酸羟化酶（TH）抗体和亮氨酸或甲硫氨酸脑啡肽（ENK）发生反应的神经元结构之间的突触关系。围绕脑啡肽免疫反应性（ENK-IR）神经元的神经胞体和近端树突的酪氨酸羟化酶免疫反应性（TH-IR）轴突终扣非常细（0.1-0.4微米）。它们含有许多小的清亮小泡，有时具有对称的膜特化结构。这为大鼠纹状体脑啡肽能神经元的儿茶酚胺能（可能是多巴胺能）输入提供了形态学证据。
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