Witkowska Anna M, Waśkiewicz Anna, Zujko Małgorzata E, Szcześniewska Danuta, Pająk Andrzej, Stepaniak Urszula, Drygas Wojciech
Department of Food Biotechnology, Medical University of Bialystok, Bialystok, Poland.
Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, National Institute of Cardiology, Warsaw, Poland.
Oxid Med Cell Longev. 2017;2017:5982809. doi: 10.1155/2017/5982809. Epub 2017 Jun 20.
The aim of the study was to assess the relationship between the dietary polyphenol intake (DPI) and the dietary total antioxidant capacity (DTAC) and the prevalence of cardiovascular disease (CVD) in postmenopausal women. Participants were 916 postmenopausal women diagnosed with CVD and 1683 postmenopausal women without history of CVD, who took part in the population-based studies carried out in Poland: WOBASZ (2003-2005) and WOBASZ II (2013-2014). Nutritional data were collected using a single 24-hour dietary recall. DPI and DTAC in the CVD women were significantly lower and accounted for 1766.39 mg/d and 10.84 mmol/d, respectively, versus 1920.57 mg/d and 11.85 mmol/d in the women without CVD, but these differences disappeared after the standardization for energy input. Also, in the multiple-adjustment model, higher DPI, but not DTAC, was associated with the reduced odds ratio for the prevalence of CVD. Beverages, mainly coffee and tea, contributed in more than 40% to DPI and in more than a half to DTAC. In this study, higher dietary polyphenol intake, but not the dietary total antioxidant capacity, was inversely associated with CVD in postmenopausal women, which points to the health benefits of increased polyphenol intake from food sources for these women.
本研究旨在评估绝经后女性的膳食多酚摄入量（DPI）与膳食总抗氧化能力（DTAC）以及心血管疾病（CVD）患病率之间的关系。参与者包括916名被诊断患有CVD的绝经后女性和1683名无CVD病史的绝经后女性，她们参与了在波兰开展的基于人群的研究：WOBASZ（2003 - 2005年）和WOBASZ II（2013 - 2014年）。通过单次24小时膳食回顾收集营养数据。患有CVD的女性的DPI和DTAC显著较低，分别为1766.39毫克/天和10.84毫摩尔/天，而无CVD的女性分别为1920.57毫克/天和11.85毫摩尔/天，但在对能量摄入进行标准化后，这些差异消失。此外，在多因素调整模型中，较高的DPI而非DTAC与CVD患病率的较低比值比相关。饮料，主要是咖啡和茶，对DPI的贡献超过40%，对DTAC的贡献超过一半。在本研究中，较高的膳食多酚摄入量而非膳食总抗氧化能力与绝经后女性的CVD呈负相关，这表明这些女性从食物来源增加多酚摄入量对健康有益。
