Wageningen University & Research, Cell Biology and Immunology, 6709 PG, Wageningen, The Netherlands.
FrieslandCampina, 3818 LE, Amersfoort, The Netherlands.
Nutrients. 2017 Jul 17;9(7):762. doi: 10.3390/nu9070762.
The development of IgE-mediated allergic diseases is influenced by many factors, including genetic and environmental factors such as pollution and farming, but also by nutrition. In the last decade, substantial progress has been made in our understanding of the impact that nutrition can have on allergic diseases. Many studies have addressed the effect of breastfeeding, pre-, pro- and synbiotics, vitamins and minerals, fiber, fruit and vegetables, cow's milk, and n-3 fatty acids, on the development of allergies. In addition, nutrition can also have indirect effects on allergic sensitization. This includes the diet of pregnant and breastfeeding women, which influences intrauterine development, as well as breastmilk composition. These include the diet of pregnant and breastfeeding women that influences intrauterine development as well as breastmilk composition, effects of food processing that may enhance allergenicity of foods, and effects via modulation of the intestinal microbiota and their metabolites. This editorial review provides a brief overview of recent developments related to nutrition and the development and management of allergic diseases.
IgE 介导的过敏性疾病的发展受多种因素影响,包括遗传和环境因素,如污染和农业,也受营养因素影响。在过去的十年中,我们对营养对过敏性疾病的影响有了更深入的了解。许多研究探讨了母乳喂养、预、益生菌和后生元、维生素和矿物质、纤维、水果和蔬菜、牛奶和 n-3 脂肪酸对过敏发展的影响。此外,营养也可以对过敏致敏产生间接影响。这包括孕妇和哺乳期妇女的饮食,会影响宫内发育和母乳成分。其中包括孕妇和哺乳期妇女的饮食会影响宫内发育和母乳成分,食物加工的影响可能会增强食物的致敏性,以及通过调节肠道微生物群及其代谢物产生的影响。本社论简要概述了与营养以及过敏性疾病的发展和管理相关的最新进展。
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