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鼻腔涂抹凡士林软膏——外源性类脂性肺炎的一个隐匿病因:泼尼松龙治疗成功

Nasal application of petrolatum ointment - A silent cause of exogenous lipoid pneumonia: Successfully treated with prednisolone.

作者信息

Kilaru Hemanth, Prasad Sudhir, Radha Sistla, Nallagonda Ravindra, Kilaru Satish Chandra, Nandury Eshwar Chandra

机构信息

Department of Respiratory Medicine, Prathima Institute of Medical Sciences, Karimnagar, Telangana, India.

Department of Pulmonary and Critical Care Medicine, Aware Global Hospital, Hyderabad, Telangana, India.

出版信息

Respir Med Case Rep. 2017 Jul 8;22:98-100. doi: 10.1016/j.rmcr.2017.07.003. eCollection 2017.

Abstract

We report a case of exogenous lipoid pneumonia from chronic, extranasal use of petrolatum ointment (Vicks VapoRub in this case) for nasal decongestion in a young woman, presenting with cough, dyspnea and fever. Exogenous Lipoid pneumonia is a rare condition, underdiagnosed and is more prevalent in adults. Usually asymptomatic and diagnosed while evaluating predisposed patients who become clinically unstable or an abnormal lung shadow or during evaluation of rhinobronchial allergy. It is rarely reported from chronic use of petrolatum ointment extranasally and was diagnosed by transbronchial biopsy in the present case. She was found, retrospectively, to have been using petrolatum ointment, as an extranasal application since more than a year at bedtime. She didn't give history of using any other oil-based nasal topical vasoconstrictor preparations for sinusitis. Our patient was managed with discontinuation of further use of the petrolatum ointment and treatment with prednisolone apart from her regular treatment for chronic rhinobronchial allergy. Patient is stable without any further radiological deterioration during follow-up of one year.

摘要

我们报告了一例年轻女性因长期在鼻外使用凡士林软膏(本病例中为维克斯伤风膏)来缓解鼻塞而导致外源性类脂性肺炎的病例,该患者表现为咳嗽、呼吸困难和发热。外源性类脂性肺炎是一种罕见疾病,诊断不足,在成年人中更为常见。通常无症状,在评估临床病情不稳定的易感患者、发现肺部异常阴影或评估鼻支气管过敏时被诊断出来。因长期鼻外使用凡士林软膏导致外源性类脂性肺炎的情况鲜有报道,本病例通过经支气管活检得以确诊。回顾发现,她一年多来每晚都在鼻外涂抹凡士林软膏。她没有使用过其他用于鼻窦炎的油基性鼻用局部血管收缩剂制剂的病史。除了对慢性鼻支气管过敏进行常规治疗外,我们的患者通过停用凡士林软膏并使用泼尼松龙进行治疗。在一年的随访中,患者病情稳定,影像学未出现进一步恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e1e/5508482/c4c6ae704b9b/gr1.jpg

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