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纳米乳剂:一种用于高效药物递送的先进载体。

Nanoemulsion: An Advanced Vehicle For Efficient Drug Delivery.

作者信息

Ali Asad, Ansari Vaseem Ahamad, Ahmad Usama, Akhtar Juber, Jahan Afroz

机构信息

Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India.

出版信息

Drug Res (Stuttg). 2017 Nov;67(11):617-631. doi: 10.1055/s-0043-115124. Epub 2017 Jul 24.

Abstract

Advanced drug delivery system has now gained preference over the conventional drug delivery system. One such research is nanoemulsion which is famous among the researchers because of ease of formation, stability, clarity, increased absorption rate leading to increasing in bioavailability and potential to form a formulation with both lipophilic as well as the hydrophilic drug. Long lasting stability (up to years) and ability to encapsulate both lipophilic and hydrophilic drug has given this colloidal system a valuable position in drug delivery. This article contains information on components required for its fabrication, preparation methods and evaluation parameters along with its application in drug delivery and future aspects of this advanced drug delivery system.

摘要

先进的药物递送系统如今已比传统药物递送系统更受青睐。纳米乳剂就是这样一项研究成果,它在研究人员中颇负盛名,原因在于其易于形成、稳定性好、澄清度高、吸收率提高从而使生物利用度增加,以及有潜力形成同时包含亲脂性药物和亲水性药物的制剂。持久的稳定性(长达数年)以及包封亲脂性药物和亲水性药物的能力,使这种胶体系统在药物递送领域占据了重要地位。本文包含了其制备所需的成分、制备方法、评价参数等信息,以及它在药物递送中的应用和这种先进药物递送系统的未来发展方向。

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