Tsui J K, Eisen A, Stoessl A J, Calne S, Calne D B
Lancet. 1986 Aug 2;2(8501):245-7. doi: 10.1016/s0140-6736(86)92070-2.
In a double-blind trial in 21 patients with spasmodic torticollis botulinum-A toxin produced both subjective and objective improvement, including significant pain relief in 14 of the 16 patients presenting with pain. Side-effects were more frequently reported during placebo administration and no significant systemic adverse reactions were noted.
在一项针对21例痉挛性斜颈患者的双盲试验中,A型肉毒杆菌毒素产生了主观和客观的改善,包括16例有疼痛症状的患者中有14例疼痛得到显著缓解。在给予安慰剂期间更常报告有副作用,未观察到明显的全身性不良反应。