传染性胰腺坏死病毒（IPNV）Sp血清型在土耳其虹鳟养殖场中很普遍。

Infectious pancreatic necrosis virus (IPNV) serotype Sp is prevalent in Turkish rainbow trout farms.

作者信息

Büyükekiz A G, Altun S, Hansen E F, Satıcıoğlu I B, Duman M, Markussen T, Rimstad E

机构信息

Department of Aquatic Animal Diseases, Faculty of Veterinary Medicine, Uludag University, Bursa, Turkey.

Department of Food Safety and Infection Biology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.

出版信息

J Fish Dis. 2018 Jan;41(1):95-104. doi: 10.1111/jfd.12675. Epub 2017 Jul 26.

DOI:10.1111/jfd.12675

PMID:28745835

Abstract

Infectious pancreatic necrosis virus (IPNV) is a common pathogen of rainbow trout (Oncorhynchus mykiss) in Turkey. We found that 455 of 1,676 sample pools tested were IPNV positive. Positive samples were found in all geographical regions where sampling was conducted. Sequence and phylogenetic analyses of VP2 from 30 isolates representing all regions showed that the viruses were highly similar in sequence and grouped within Genogroup 5 (serotype Sp-A2). No correlations between sequences, sampling sites or geographical origins were identified. Although clinical disease was evident in several farms, analyses of the amino acid sequence of VP2 showed that all virus strains harboured the P T motif, assumed to be associated with low virulence. We conclude that IPNV is prevalent in Turkish rainbow trout farms and that the viruses are very homogenous and likely to be of European origin. Frequent exchange of eggs and live fish within the farming industry may explain the homogeneity of the IPNV.

摘要

传染性胰腺坏死病毒（IPNV）是土耳其虹鳟（Oncorhynchus mykiss）的常见病原体。我们发现，在检测的1676个样本池中，有455个呈IPNV阳性。在所有进行采样的地理区域均发现了阳性样本。对代表所有区域的30个分离株的VP2进行序列和系统发育分析表明，这些病毒在序列上高度相似，归为基因群5（血清型Sp-A2）。未发现序列、采样地点或地理来源之间存在相关性。尽管在几个养殖场明显出现了临床疾病，但对VP2氨基酸序列的分析表明，所有病毒株都含有假定与低毒力相关的PT基序。我们得出结论，IPNV在土耳其虹鳟养殖场中普遍存在，并且这些病毒非常同源，可能起源于欧洲。养殖行业内鱼卵和活鱼的频繁交换可能解释了IPNV的同源性。