Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital, 700 Children's Dr, Columbus, OH, 43205, USA.
Department of Pediatrics, College of Medicine, The Ohio State University, 700 Children's Dr, Columbus, OH, 43205, USA.
J Autism Dev Disord. 2017 Nov;47(11):3358-3369. doi: 10.1007/s10803-017-3249-3.
Delayed language development may be an early indicator of autism spectrum disorder (ASD). Early intervention is critical for children with ASD, and the present study presents pilot data on a clinical trial of omega-3 and -6 fatty acid supplementation and language development, a secondary trial outcome, in children at risk for ASD. We randomized 31 children to receive an omega-3 and -6 supplement or a placebo for 3 months, and measured their language abilities at baseline and after supplementation. Gesture use, but not word production, increased for children in the treatment group more than children in the placebo group. These results suggest possible effectiveness of omega-3 and -6 supplementation for language development in children at risk for ASD.
语言发育迟缓可能是自闭症谱系障碍（ASD）的早期指标。早期干预对 ASD 儿童至关重要，本研究介绍了一项关于ω-3 和 ω-6 脂肪酸补充剂和语言发育的临床试验的初步数据，这是次要的试验结果，针对有 ASD 风险的儿童。我们将 31 名儿童随机分为接受 ω-3 和 ω-6 补充剂或安慰剂的组，在基线和补充后测量他们的语言能力。与安慰剂组相比，治疗组的儿童手势使用增加，而词汇产生增加较少。这些结果表明，ω-3 和 ω-6 补充剂对有 ASD 风险的儿童的语言发育可能有效。
