1 Unité Fonctionnelle Mémoire et Maladies Neurodégénératives, Service de Neurologie, CHU Avicenne, Assistance Publique des Hôpitaux de Paris (AP-HP), Bobigny, France.
2 Laboratoire PSITEC, EA 4072, UFR de psychologie, Université Lille 3, Pont de Bois, Villeneuve d'Ascq, France.
Am J Alzheimers Dis Other Demen. 2017 Dec;32(8):461-467. doi: 10.1177/1533317517722630. Epub 2017 Jul 27.
The present study aimed at validating the Memory Associative Test of the district of Seine-Saint-Denis (TMA)-93, a new test of episodic memory. The TMA-93 was proposed to mostly less educated and multicultural elderly population composed of 376 healthy controls (HC) and 94 patients with Alzheimer's disease (AD). The construct validity was checked by studying correlations with a widely used memory test (the Free and Cued Selective Reminding Test [FCSRT]) in the subsample of literate patients. Results showed that (i) all the TMA-93 scores of the patients with AD were lower than those of the HC, (ii) the TMA-93 total score identified patients with AD with a high sensitivity (88%) and very high specificity (97%), and (iii) the TMA-93 total score was strongly correlated with both free recall and total recall scores of the FCSRT. Taken together, results showed that the TMA-93 is a reliable tool to assess episodic memory in a multicultural, less educated, or illiterate population, with good construct validity for AD diagnostic accuracy.
本研究旨在验证塞纳-圣但尼地区（93 区）记忆联想测试（TMA-93）的有效性，这是一种新的情景记忆测试。TMA-93 主要针对受教育程度较低和多元文化的老年人群，其中包括 376 名健康对照者（HC）和 94 名阿尔茨海默病（AD）患者。在有文化的患者亚组中，通过研究与广泛使用的记忆测试（自由和线索选择性提醒测试[FCSRT]）的相关性来检查结构效度。结果表明：（i）AD 患者的所有 TMA-93 评分均低于 HC，（ii）TMA-93 总分对 AD 患者具有较高的敏感性（88%）和极高的特异性（97%），（iii）TMA-93 总分与 FCSRT 的自由回忆和总回忆得分均呈强相关。总之，结果表明 TMA-93 是一种可靠的工具，可用于评估受教育程度较低、多元文化或文盲人群的情景记忆，对 AD 的诊断准确性具有良好的结构效度。
