药物、细菌和癌症：具核梭杆菌促进结直肠癌的化疗耐药性。
Drugs, Bugs, and Cancer: Fusobacterium nucleatum Promotes Chemoresistance in Colorectal Cancer.
机构信息
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
出版信息
Cell. 2017 Jul 27;170(3):411-413. doi: 10.1016/j.cell.2017.07.018.
The tumor microenvironment has recently been shown to play decisive roles in chemotherapeutic response. In this issue of Cell, Yu et al. add to these findings by identifying the bacterium Fusobacterium nucleatum as a previously unrecognized chemoresistance mediator in colorectal cancer, thereby establishing the microbiota as a potential therapeutic target.
肿瘤微环境最近被证明在化疗反应中起着决定性的作用。在本期《细胞》杂志上，于等研究人员的研究进一步证实，梭杆菌属(Fusobacterium nucleatum)是结直肠癌中一种以前未被识别的化疗耐药介质，从而将微生物组确立为一个潜在的治疗靶点。
Zotero 插件