Williamson Victoria, Coetzee Bronwyne, Kagee Ashraf, Tomlinson Mark
Department of Psychology, University of Bath - Claverton Down, Bath, Bath BA2 7AY, UK.
Department of Psychology, Stellenbosch University - RW Wilcocks Building, Ryneveld Street, Stellenbosch 7600, South Africa.
Future Virol. 2017 Jan;12(1):19-28. doi: 10.2217/fvl-2016-0090. Epub 2016 Dec 21.
Despite advances in preventive treatments for HIV, children continue to become infected with HIV. Research has investigated adult and adolescents' willingness to participate in hypothetical HIV vaccine trials; however, maternal willingness to enroll their infants in such trials remains underexplored.
This study explored the factors influencing mothers' decision-making about enrolling their HIV negative infants in a hypothetical HIV vaccine trial. Methods: HIV infected and uninfected mothers (n = 22) were interviewed.
Several factors were identified as influencing the mothers' decisions, including perceptions and knowledge of HIV and vaccines.
Maternal concerns about protecting their infants from HIV were also identified and mothers indicated that they were eager to vaccinate their children. Insufficient information and reassurance regarding vaccine trial safety and efficacy influenced maternal reluctance to enroll their child.
尽管在艾滋病毒预防性治疗方面取得了进展，但儿童仍不断感染艾滋病毒。已有研究调查了成人和青少年参与假设性艾滋病毒疫苗试验的意愿；然而，母亲让其婴儿参与此类试验的意愿仍未得到充分探讨。
本研究探讨了影响母亲决定让其艾滋病毒阴性婴儿参与假设性艾滋病毒疫苗试验的因素。方法：对感染和未感染艾滋病毒的母亲（n = 22）进行了访谈。
确定了几个影响母亲决定的因素，包括对艾滋病毒和疫苗的认知及知识。
还确定了母亲对保护婴儿免受艾滋病毒感染的担忧，母亲表示她们渴望为孩子接种疫苗。关于疫苗试验安全性和有效性的信息不足及缺乏保证影响了母亲让孩子参与试验的意愿。
