Emerg Infect Dis. 2017 Oct;23(10):1718-21. doi: 10.3201/eid2310.170834. Epub 2017 Oct 17.
We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolongation but no arrhythmias occurred. Use of this therapy is justified for patients with limited options.
我们报告了 5 例服用贝达喹啉联合德拉马尼的患者的经验:1 例治愈;3 例培养转换,其中 2 例继续治疗,1 例改变治疗方案;1 例死于呼吸功能不全。有 2 例患者出现 QT 间期延长但无心律失常。对于选择有限的患者,这种治疗方法是合理的。