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[酒精性肝病危险因素的研究进展]

[Research advances in risk factors for alcoholic liver disease].

作者信息

Xu B B, Li Y L, Wang B Y

机构信息

Department of Elderly Gastroenterology, The First Affiliated Hospital, China Medical University, Shenyang 110001, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2017 May 20;25(5):397-400. doi: 10.3760/cma.j.issn.1007-3418.2017.05.019.

DOI:10.3760/cma.j.issn.1007-3418.2017.05.019
PMID:28763852
Abstract

Only a small number of people may develop severe alcoholic liver disease after continuous or excessive drinking, which is different from the harm caused by smoking, and some people may even develop alcoholic liver disease associated with inflammation, liver cirrhosis, or primary liver cancer. There are complex risk factors for liver injury in these people; besides ethnic and genetic factors, drinking volume, and drinking duration, more important factors are involved in the pathophysiological changes of the liver, such as the type and quality of alcohol, drinking pattern, socioeconomic status, and government public policy, which may be the determining factors for the development of alcoholic liver disease. On the basis of literature review, this article proposes the concept that "liquor does not equal to alcohol" , which has important guiding significance for healthy drinking and the prevention of alcoholic liver disease.

摘要

只有一小部分人在持续或过量饮酒后可能会发展为严重的酒精性肝病,这与吸烟造成的危害不同,有些人甚至可能发展为伴有炎症、肝硬化或原发性肝癌的酒精性肝病。这些人肝脏损伤存在复杂的危险因素;除了种族和遗传因素、饮酒量和饮酒持续时间外,更重要的因素还涉及肝脏的病理生理变化,如酒精的类型和质量、饮酒方式、社会经济地位以及政府公共政策等,这些可能是酒精性肝病发生发展的决定性因素。在文献综述的基础上,本文提出“白酒不等于酒精”这一概念,对健康饮酒及预防酒精性肝病具有重要的指导意义。

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[Research advances in risk factors for alcoholic liver disease].[酒精性肝病危险因素的研究进展]
Zhonghua Gan Zang Bing Za Zhi. 2017 May 20;25(5):397-400. doi: 10.3760/cma.j.issn.1007-3418.2017.05.019.
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Prevalence and natural history of alcoholic liver disease.酒精性肝病的患病率和自然史。
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Alcohol Policies and Alcohol-related Liver Disease Mortality.酒精政策与酒精性肝病死亡率
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Consumption of 'country liquor' and its relation to alcoholic liver disease in Mumbai.孟买地区“乡村酒”的消费情况及其与酒精性肝病的关系。
J Assoc Physicians India. 1998 Jun;46(6):510-3.
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Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group.饮酒习惯作为酒精性肝损伤风险的辅助因素。狄俄尼索斯研究小组。
Gut. 1997 Dec;41(6):845-50. doi: 10.1136/gut.41.6.845.
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Profile of alcoholic liver disease in an Indian hospital. A prospective analysis.
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Epidemiology of alcoholic liver disease.酒精性肝病的流行病学
Semin Liver Dis. 1988 Feb;8(1):12-25. doi: 10.1055/s-2008-1040525.

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