Karkuzhali Ponnuswamy, Yogambal Muthureddy, Kumar Manoj
Former Director, Department of Pathology, Madras Medical College, Chennai, Tamilnadu, India.
Assistant Professor, Department of Pathology, Stanley Medical College, Chennai, Tamilnadu, India.
J Clin Diagn Res. 2017 Jun;11(6):EC26-EC29. doi: 10.7860/JCDR/2017/27673.10095. Epub 2017 Jun 1.
Thyroid carcinoma is the most common endocrine malignancy and its Papillary Histotype {Papillary Carcinoma of Thyroid (PTC)} is the most common type of Thyroid cancer. The clinicopathological features of PTC vary with geographical location.
To describe the clinicopathological profile of PTC in a Tertiary Care Hospital located in Chennai, Tamil Nadu, India.
Data on age, sex, centricity of the tumour, presence of calcifications, infiltration, metastasis, associated non malignant conditions and frequency of histological subtypes of all cases of PTC diagnosed in Department of Pathology, Madras Medical College Chennai, Tamil Nadu, India between January 2007 and December 2011 were obtained from clinicopathological documents and analysed statistically.
Statistically significant correlations were found between age and sex, age and metastasis, sex and centricity, sex and metastasis, size of lesion and sex, size of lesion and age, size and presence of calcifications and presence of calcifications and metastasis.
Scenario of PTC in our tertiary care setup which warrants attention is male preponderance of multicentric lesions. Further, a high association with colloid nodular goitre, while low incidence of tall cell variant is notable clinico pathological scenarios in this study.
甲状腺癌是最常见的内分泌恶性肿瘤，其乳头状组织学类型（甲状腺乳头状癌，PTC）是甲状腺癌最常见的类型。PTC的临床病理特征因地理位置而异。
描述位于印度泰米尔纳德邦金奈的一家三级护理医院中PTC的临床病理特征。
从印度泰米尔纳德邦金奈马德拉斯医学院病理科2007年1月至2011年12月诊断的所有PTC病例的临床病理文件中获取有关年龄、性别、肿瘤中心性、钙化情况、浸润、转移、相关非恶性疾病以及组织学亚型频率的数据，并进行统计分析。
发现年龄与性别、年龄与转移、性别与中心性、性别与转移、病变大小与性别、病变大小与年龄、大小与钙化情况以及钙化情况与转移之间存在统计学上的显著相关性。
在我们的三级护理机构中，PTC值得关注的情况是多中心病变以男性居多。此外，与胶样结节性甲状腺肿高度相关，而高细胞变体的低发生率是本研究中值得注意的临床病理情况。
