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扎恩绘图:用于颅面发育研究的胚胎和蝌蚪阶段的新插图。

The Zahn drawings: new illustrations of embryo and tadpole stages for studies of craniofacial development.

作者信息

Zahn Natalya, Levin Michael, Adams Dany Spencer

机构信息

www.natalya.com, Cambridge, MA, USA.

Department of Biology and Tufts Center for Regenerative and Developmental Biology, Tufts University, Medford, MA 02155, USA.

出版信息

Development. 2017 Aug 1;144(15):2708-2713. doi: 10.1242/dev.151308.

Abstract

The embryos and tadpoles of the frog are increasingly important subjects for studies of the development of the head and face - studies that are providing novel and crucial insight into the causes and prevention of a suite of devastating birth defects, as well as basic evolutionary and developmental biology. However, many studies are conducted on a range of embryonic stages that are not fully represented in the beloved resource, Nieuwkoop and Faber's classic Xenopus laevis The lack of standardized images at these stages acts as a barrier to the efficient and accurate representation and communication of experimental methodology and expression data. To fill this gap, we have created 27 new high-quality illustrations. Like their oft-used predecessors from Nieuwkoop and Faber, these drawings can be freely downloaded and used, and will, we hope, serve as an essential resource for this important model system.

摘要

青蛙的胚胎和蝌蚪对于头部和面部发育的研究愈发重要——这些研究为一系列严重出生缺陷的成因及预防,以及基础进化生物学和发育生物学提供了全新且关键的见解。然而,许多研究是在一系列胚胎阶段上进行的,而备受喜爱的资源——尼乌科普(Nieuwkoop)和法伯(Faber)的经典《非洲爪蟾》(Xenopus laevis)中并未充分呈现这些阶段。这些阶段缺乏标准化图像,成为了高效、准确地呈现和交流实验方法及表达数据的障碍。为填补这一空白,我们创作了27幅新的高质量插图。与尼乌科普和法伯常用的前辈插图一样,这些绘图可免费下载和使用,我们希望它们能成为这个重要模型系统的重要资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/5560046/e69edb38be7f/develop-144-151308-g1.jpg

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