Mesic Anita, Fontaine Julie, Aye Theingy, Greig Jane, Thwe Thin Thin, Moretó-Planas Laura, Kliesckova Jarmila, Khin Khin, Zarkua Nana, Gonzalez Lucia, Guillergan Erwin Lloyd, O'Brien Daniel P
Médecins Sans Frontières, Operational Center Amsterdam, The Netherlands.
Médecins Sans Frontières, Operational Center Amsterdam, Yangon, Myanmar.
J Int AIDS Soc. 2017 Jul 21;20(Suppl 4):21644. doi: 10.7448/IAS.20.5.21644.
National AIDS Programme in Myanmar has made significant progress in scaling up antiretroviral treatment (ART) services and recognizes the importance of differentiated care for people living with HIV. Indeed, long centred around the hospital and reliant on physicians, the country's HIV response is undergoing a process of successful decentralization with HIV care increasingly being integrated into other health services as part of a systematic effort to expand access to HIV treatment. This study describes implementation of differentiated care in Médecins Sans Frontières (MSF)-supported programmes and reports its outcomes.
A descriptive cohort analysis of adult patients on antiretroviral treatment was performed. We assessed stability of patients as of 31 December 2014 and introduced an intervention of reduced frequency of physicians' consultations for stable patients, and fast tract ART refills. We measured a number of saved physician's visits as the result of this intervention. Main outcomes, remained under care, death, lost to follow up, treatment failure, were assessed on 31 December 2015 and reported as rates for different stable groups.
On 31 December 2014, our programme counted 16, 272 adult patients enrolled in HIV care, of whom 80.34% were stable. The model allowed for an increase in the average number of patients one medical team could care for - from 745 patients in 2011 to 1, 627 in 2014 - and, thus, a reduction in the number of teams needed. An assessment of stable patients enrolled on ART one year after the implementation of the new model revealed excellent outcomes, aggregated for stable patients as 98.7% remaining in care, 0.4% dead, 0.8% lost to follow-up, 0.8% clinical treatment failure and 5.8% with immunological treatment failure.
Implementation of a differentiated model reduced the number of visits between stable clients and physicians, reduced the medical resources required for treatment and enabled integrated treatment of the main co-morbidities. We hope that these findings will encourage other stakeholders to implement innovative models of HIV care in Myanmar, further expediting the scale up of ART services, the decentralization of treatment and the integration of care for the main HIV co-morbidities in this context.
缅甸国家艾滋病项目在扩大抗逆转录病毒治疗(ART)服务方面取得了重大进展,并认识到为艾滋病毒感染者提供差异化护理的重要性。实际上,该国的艾滋病毒应对工作长期以来以医院为中心且依赖医生,目前正在经历一个成功的权力下放过程,艾滋病毒护理越来越多地融入其他卫生服务,作为扩大艾滋病毒治疗可及性系统努力的一部分。本研究描述了无国界医生组织(MSF)支持项目中差异化护理的实施情况并报告了其结果。
对接受抗逆转录病毒治疗的成年患者进行描述性队列分析。我们评估了截至2014年12月31日患者的稳定性,并对病情稳定的患者实施了减少医生会诊频率以及快速补充抗逆转录病毒治疗药物的干预措施。我们测量了由于该干预措施而节省的医生出诊次数。主要结局指标,即仍在接受治疗、死亡、失访、治疗失败,于2015年12月31日进行评估,并报告为不同稳定组别的发生率。
截至2014年12月31日,我们的项目有16272名成年患者登记接受艾滋病毒护理,其中80.34%病情稳定。该模式使一个医疗团队能够护理的患者平均数量有所增加——从2011年的745名患者增加到2014年的1627名——因此所需的团队数量减少。对新模式实施一年后登记接受抗逆转录病毒治疗的稳定患者进行的评估显示结果良好,稳定患者的汇总情况为98.7%仍在接受治疗,0.4%死亡,0.8%失访,0.8%临床治疗失败,5.8%免疫治疗失败。
实施差异化模式减少了病情稳定的患者与医生之间的就诊次数,减少了治疗所需的医疗资源,并实现了主要合并症的综合治疗。我们希望这些发现将鼓励其他利益相关者在缅甸实施创新的艾滋病毒护理模式,进一步加快抗逆转录病毒治疗服务的扩大、治疗的权力下放以及在此背景下艾滋病毒主要合并症护理的整合。