Habtewold Tesfa Dejenie, Islam Md Atiqul, Sharew Nigussie Tadesse, Mohammed Shimels Hussien, Birhanu Mulugeta Molla, Tegegne Balewgizie Sileshi
Department of Nursing, Debre Berhan University, Debre Berhan, Ethiopia.
Department of Epidemiology and Rob Giel Research Centre, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
BMJ Open. 2017 Aug 3;7(8):e017437. doi: 10.1136/bmjopen-2017-017437.
Infant and young child feeding (IYCF) is the cornerstone of infant and child survival, healthy growth and development, healthy future generations and national development. In spite of the importance of optimal nutrition in low- and middle-income countries, there has been no review conducted in Ethiopia. Thus, the aim of this systematic review and meta-analysis is to estimate the national coverage and identify the associated factors of IYCF practices in Ethiopia.
PubMed, Scopus, EMBASE, CINHAL, EBSCO, Web of Science and WHO Global Health Library databases will be searched for all available publications from 1 January 2000 to 30 September 2017. All published studies on the timely initiation of breast feeding, exclusive breast feeding and timely initiation of complementary feeding practice in Ethiopia will be screened, selected and reviewed. Bibliographies of identified articles and grey literature will be hand-searched as well. Heterogeneity of studies will be quantified using Higgins's method where I statistic >80% indicates substantial heterogeneity. Funnel plots and Egger's regression test will be used to assess potential publication bias. The Newcastle-Ottawa Scale (NOS) will be used to assess the quality of evidence and risk of bias. Meta-analysis and meta-regression will be carried out to estimate the pooled national prevalence rate and an OR of each associated factor of IYCF practices. Narrative synthesis will be performed if meta-analysis is not feasible due to the substantial heterogeneity of studies.
Ethical clearance is not required for this study because primary data will not be collected. The results of this systematic review and meta-analysis will be published in a peer-reviewed journal and presented at an (inter)national research symposium.
This systematic review and meta-analysis has been registered with the International Prospective Register of Systematic Reviews (PROSPERO), registration number CRD42017056768.
婴幼儿喂养是婴幼儿生存、健康成长与发育、子孙后代健康以及国家发展的基石。尽管在低收入和中等收入国家，最佳营养至关重要，但埃塞俄比亚尚未进行过相关综述。因此，本系统综述和荟萃分析的目的是评估埃塞俄比亚婴幼儿喂养做法的全国覆盖率，并确定相关因素。
将检索PubMed、Scopus、EMBASE、CINHAL、EBSCO、Web of Science和世界卫生组织全球健康图书馆数据库，以获取2000年1月1日至2017年9月30日期间的所有可用出版物。将筛选、选择和综述所有已发表的关于埃塞俄比亚母乳喂养的及时开始、纯母乳喂养和辅食添加及时开始做法的研究。还将人工检索已识别文章的参考文献和灰色文献。将使用希金斯方法对研究的异质性进行量化，其中I统计量>80%表示存在实质性异质性。将使用漏斗图和埃格回归检验来评估潜在的发表偏倚。将使用纽卡斯尔-渥太华量表（NOS）来评估证据质量和偏倚风险。将进行荟萃分析和荟萃回归，以估计汇总的全国患病率以及婴幼儿喂养做法各相关因素的比值比。如果由于研究的实质性异质性而无法进行荟萃分析，则将进行叙述性综合分析。
本研究无需伦理批准，因为不会收集原始数据。本系统综述和荟萃分析的结果将发表在同行评审期刊上，并在（国际）研究研讨会上展示。
本系统综述和荟萃分析已在国际系统综述前瞻性注册库（PROSPERO）注册，注册号为CRD42017056768。
