弗瑞德氏鼠白血病病毒在造血系统肿瘤中整合的一个优先区域与Int-2癌基因紧密相连。
A preferred region for integration of Friend murine leukemia virus in hematopoietic neoplasms is closely linked to the Int-2 oncogene.
作者信息
Silver J, Buckler C E
出版信息
J Virol. 1986 Dec;60(3):1156-8. doi: 10.1128/JVI.60.3.1156-1158.1986.
Abstract
Gene mapping experiments show that Fis-1, a preferred integration region for Friend murine leukemia virus in hematopoietic neoplasms, is extremely closely linked to Int-2, a preferred integration region for mouse mammary tumor virus in mammary carcinomas. Studies at the RNA and DNA level prove that these loci are distinct.
摘要
基因定位实验表明，Fis-1是造血系统肿瘤中Friend鼠白血病病毒的一个优先整合区域，它与Int-2紧密连锁，而Int-2是乳腺癌中小鼠乳腺肿瘤病毒的一个优先整合区域。在RNA和DNA水平上的研究证明这些基因座是不同的。
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