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基于葡萄糖对 MoS₂ 上胶体银纳米粒子电化学行为的调控作用的高灵敏度非酶葡萄糖生物传感器。

A Highly Sensitive Nonenzymatic Glucose Biosensor Based on the Regulatory Effect of Glucose on Electrochemical Behaviors of Colloidal Silver Nanoparticles on MoS₂†.

机构信息

Department of Chemistry, Idaho State University, Pocatello, ID 83201, USA.

Department of Anthropology, Idaho State University, Pocatello, ID 83201, USA.

出版信息

Sensors (Basel). 2017 Aug 5;17(8):1807. doi: 10.3390/s17081807.

Abstract

A novel and highly sensitive nonenzymatic glucose biosensor was developed by nucleating colloidal silver nanoparticles (AgNPs) on MoS₂. The facile fabrication method, high reproducibility (97.5%) and stability indicates a promising capability for large-scale manufacturing. Additionally, the excellent sensitivity (9044.6 μA mM cm), low detection limit (0.03 μM), appropriate linear range of 0.1-1000 μM, and high selectivity suggests that this biosensor has a great potential to be applied for noninvasive glucose detection in human body fluids, such as sweat and saliva.

摘要

一种新型的、高灵敏度的非酶葡萄糖生物传感器是通过在 MoS₂ 上成核胶体银纳米粒子(AgNPs)制备而成的。该传感器具有制备方法简单、重现性好(97.5%)、稳定性高的特点,表明其具有大规模生产的潜力。此外,该传感器具有优异的灵敏度(9044.6 μA mM cm)、低检测限(0.03 μM)、合适的线性范围(0.1-1000 μM)和较高的选择性,表明该生物传感器在人体液如汗液和唾液的无创性葡萄糖检测方面具有很大的应用潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf7f/5579834/e373ade91b63/sensors-17-01807-g001.jpg

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