Keck's Advanced Materials Laboratory, Manufacturing Systems Engineering &Management, California State University of Northridge, Northridge, California, United States of America.
Corrosion Research Laboratory, Manufacturing Systems Engineering &Management, California State University of Northridge, Northridge, California, United States of America.
Sci Rep. 2016 Jun 16;6:27975. doi: 10.1038/srep27975.
A novel and highly sensitive disposable glucose sensor strip was developed using direct laser engraved graphene (DLEG) decorated with pulse deposited copper nanocubes (CuNCs). The high reproducibility (96.8%), stability (97.4%) and low cost demonstrated by this 3-step fabrication method indicates that it could be used for high volume manufacturing of disposable glucose strips. The fabrication method also allows for a high degree of flexibility, allowing for control of the electrode size, design, and functionalization method. Additionally, the excellent selectivity and sensitivity (4,532.2 μA/mM.cm(2)), low detection limit (250 nM), and suitable linear range of 25 μM-4 mM, suggests that these sensors may be a great potential platform for glucose detection within the physiological range for tear, saliva, and/or sweat.
一种新颖且高灵敏度的一次性葡萄糖传感器条是使用直接激光刻蚀的石墨烯（DLEG）和脉冲沉积的铜纳米立方体（CuNCs）制备的。这种 3 步制造方法具有很高的重现性（96.8%）、稳定性（97.4%）和低成本，表明它可以用于大量制造一次性葡萄糖条。该制造方法还具有很高的灵活性，允许控制电极的大小、设计和功能化方法。此外，优异的选择性和灵敏度（4532.2 μA/mM·cm2）、低检测限（250 nM）和合适的线性范围为 25 μM-4 mM，表明这些传感器可能是检测泪液、唾液和/或汗液中生理范围内葡萄糖的一个很有潜力的平台。
