Precision Livestock and Nutrition Unit, Gembloux Agro-Bio Tech, TERRA, Teaching and Research Centre, University of Liège, 5030, Gembloux, Belgium.
Research Foundation for Industry and Agriculture, National Scientific Research Foundation (FRIA-FNRS), Brussels, Belgium.
Sci Rep. 2017 Aug 7;7(1):7426. doi: 10.1038/s41598-017-07228-2.
Reaching a beneficial intestinal microbiota early in life is desirable for piglets, as microbiota will impact their future health. One strategy to achieve this is the addition of prebiotics to sows' diet, as their microbiota will be transferred. Transmission of microbiota to the offspring occurs at birth and during lactation but a transfer might also occur during gestation. The objectives of this study were to determine whether and when (before and/or after birth) a maternal transfer of the microbiota occurs, and to observe the impact of wheat bran (WB) in sows' diet on their faecal microbiota, their offspring's microbiota and fermentation profile. Sequencing was performed on DNA extracted from umbilical cord blood, meconium, sows' faeces and piglets' colon content. Short-chain fatty acid production was determined in piglets' distal gut. Different bacteria (mostly Proteobacteria, followed by Firmicutes) were found in the umbilical cord blood, suggesting a maternal transfer occurring already during gestation. Less butyrate was produced in the caecum of WB piglets and a lower concentration of valerate was observed in all intestinal parts of WB piglets. Maternal wheat bran supplementation affected microbiota of sows and piglets differently.
尽早在生命早期获得有益的肠道微生物群对仔猪是有利的，因为微生物群将影响它们未来的健康。实现这一目标的一种策略是在母猪的饮食中添加益生元，因为它们的微生物群将被转移。微生物群向后代的转移发生在出生时和哺乳期，但也可能在妊娠期发生。本研究的目的是确定是否以及何时（出生前和/或出生后）发生母体微生物群转移，并观察小麦麸皮（WB）在母猪饮食中的作用对其粪便微生物群、后代微生物群和发酵谱的影响。从脐带血、胎粪、母猪粪便和仔猪结肠内容物中提取 DNA 进行测序。在仔猪的远端肠道中测定短链脂肪酸的产生。在脐带血中发现了不同的细菌（主要是变形菌门，其次是厚壁菌门），这表明母体转移已经发生在妊娠期。WB 仔猪盲肠中丁酸的产量较低，所有肠段中戊酸盐的浓度也较低。母体小麦麸皮补充剂对母猪和仔猪的微生物群有不同的影响。
