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阿魏属生物活性成分的最新进展

Recent Advances on Bioactive Constituents in Ferula.

机构信息

Key Laboratory at Universities of Xinjiang Uygur Autonomous Region for Oasis Agricultural Pest Management and Plant Protection Resource Utilization, College of Agricultural, Shihezi University, Shihezi, 832002, China.

出版信息

Drug Dev Res. 2017 Nov;78(7):321-331. doi: 10.1002/ddr.21402. Epub 2017 Aug 8.

DOI:10.1002/ddr.21402
PMID:28786182
Abstract

Preclinical Research The genus Ferula (Umbelliferea) is widely distributed across Central Asia and the Mediterranean. Some plants of the genus Ferula have been used as sources of pharmaceuticals for centuries. Ferula is a rich source of biologically active compounds, including coumarin derivatives, sesquiterpene-substituted compounds, daucane esters, humulane, and germacrane compounds, aromatic lactones and disulfide compounds. Therefore, utilizing these bioactive constituents with antimicrobial and insecticidal effects not only can provide a new strategy for developing drug and green pesticide, but also protect endangered plant resources. In the present review, research advances on the bioactive constituents of the genus Ferula the plant sources. Drug Dev Res 78 : 321-331, 2017. © 2017 Wiley Periodicals, Inc.

摘要

基础研究 阿魏属(伞形科)广泛分布于中亚和地中海地区。该属的一些植物已被几个世纪以来用作药物来源。阿魏属是生物活性化合物的丰富来源,包括香豆素衍生物、倍半萜取代化合物、胡萝卜烷酯、葎草酮和大根香叶烯化合物、芳香内酯和二硫化物化合物。因此,利用具有抗菌和杀虫作用的这些生物活性成分不仅可以为开发药物和绿色农药提供新策略,还可以保护濒危植物资源。在本综述中,研究了阿魏属植物来源的生物活性成分的研究进展。药物开发研究 78:321-331,2017. © 2017 威利父子公司

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