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中国植物的化学成分、生物活性及其质量标志物(Q-标志物)预测:综述。

Chemistry, Bioactivity, and Prediction of the Quality Marker (Q-Marker) of Plants in China: A Review.

机构信息

International Cooperation Base for Active Substances in Traditional Chinese Medicine in Hubei Province, School of Pharmaceutical Sciences, South-Central Minzu University, 182 Min-Zu Road, Wuhan 430074, China.

College of Biological and Geographical Sciences, Yili Normal University, Yining 835000, China.

出版信息

Molecules. 2023 Jul 4;28(13):5191. doi: 10.3390/molecules28135191.

Abstract

The genus of belongs to the family Apiaceae, and many plants are used as traditional Chinese medicines. plants were initially identified as early as the "Newly Revised Materia Medica" written in the Tang Dynasty (AD 659), and several of them are also recognized as the traditional medicines of the Uygur, Kazakh, and Mongolian. plants are distributed in China, Russia, India, Africa, Central Asia, and other places. Currently, the chemical components derived from plants are mainly coumarins, sesquiterpenes, and volatile oils. plants can exhibit diverse pharmacological activities such as anti-allergy, analgesia, relieving cough, anticoagulation, and anti-tumor. Therefore, this article summarized the domestic research conducted on the genus , appropriately combines the research status of the foreign genus , and describes the chemical composition, biological activity, toxicity issues, and Q-marker prediction. In addition, all the related studies about the genus are summarized by analyzing the various databases such as CNKI, Wanfang data, PubChem and SciFinder.

摘要

属于伞形科,许多植物被用作中药。早在唐代(公元 659 年)所著的《新修本草》中就首次对植物进行了鉴定,其中一些也被认定为维吾尔族、哈萨克族和蒙古族的传统药物。植物分布在中国、俄罗斯、印度、非洲、中亚等地。目前,从植物中提取的化学成分为香豆素、倍半萜和挥发油。植物具有多种药理活性,如抗过敏、镇痛、止咳、抗凝和抗肿瘤。因此,本文对属进行了综述,适当结合了国外属的研究现状,描述了化学成分、生物活性、毒性问题和 Q-标志物预测。此外,通过分析中国知网、万方数据、PubChem 和 SciFinder 等各种数据库,对属的相关研究进行了总结。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f9/10343754/93cae9a2a3df/molecules-28-05191-g001.jpg

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