Wong Hang S, Williams Adrian J, Mok YingJuan
aSleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK bChangi General Hospital, Simei, Singapore cKing's College London, London, UK.
Curr Opin Pulm Med. 2017 Nov;23(6):517-521. doi: 10.1097/MCP.0000000000000421.
Although obstructive sleep apnea (OSA)-associated pulmonary hypertension is not uncommon and carries a worse prognosis if left untreated, it is less well recognized by clinicians. This review provides information on prevalence, pathophysiology, clinical presentation, treatment, and prognosis of pulmonary hypertension in OSA.
The prevalence of pulmonary hypertension in OSA ranges from 17 to 53%. The underlying pathophysiology is complex and yet to be fully understood. Continuous positive airway pressure has been proven to be efficacious in the treatment of OSA-associated pulmonary hypertension.
There is still lack of research in this field. We look forward to more well designed studies to help us understand this disease entity better.
尽管阻塞性睡眠呼吸暂停（OSA）相关的肺动脉高压并不少见，若不治疗预后较差，但临床医生对其认识不足。本综述提供有关OSA中肺动脉高压的患病率、病理生理学、临床表现、治疗及预后的信息。
OSA中肺动脉高压的患病率为17%至53%。其潜在的病理生理学很复杂，尚未完全明确。持续气道正压通气已被证明对治疗OSA相关的肺动脉高压有效。
该领域仍缺乏研究。我们期待有更多设计良好的研究，以帮助我们更好地了解这一疾病实体。
