Quartarone Angelo, Rizzo Vincenzo, Terranova Carmen, Cacciola Alberto, Milardi Demetrio, Calamuneri Alessandro, Chillemi Gaetana, Girlanda Paolo
Department of Biomedical, Dental Sciences and Morphological and Functional Images, University of MessinaMessina, Italy.
Centro Neurolesi Bonino Pulejo (IRCCS)Messina, Italy.
Front Neurosci. 2017 Jul 25;11:423. doi: 10.3389/fnins.2017.00423. eCollection 2017.
Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are non-invasive methods for stimulating cortical neurons that have been increasingly used in the neurology realm and in the neurosciences applied to movement disorders. In addition, these tools have the potential to be delivered as clinically therapeutic approach. Despite several studies support this hypothesis, there are several limitations related to the extreme variability of the stimulation protocols, clinical enrolment and variability of rTMS and tDCS after effects that make clinical interpretation very difficult. Aim of the present study will be to critically discuss the state of art therapeutically applications of rTMS and tDCS in dystonia.
重复经颅磁刺激（rTMS）和经颅直流电刺激（tDCS）是刺激皮层神经元的非侵入性方法，已越来越多地应用于神经病学领域以及应用于运动障碍的神经科学中。此外，这些工具有可能作为临床治疗方法使用。尽管有几项研究支持这一假设，但由于刺激方案的极端变异性、临床入组情况以及rTMS和tDCS后效应的变异性，存在一些局限性，这使得临床解读非常困难。本研究的目的将是批判性地讨论rTMS和tDCS在肌张力障碍治疗应用方面的现状。
