Srivastava Pooja, Sreekrishnan T R, Nema A K
Department of Civil Engineering, Indian Institute of Technology Delhi, New Delhi, India, Hauz Khas, New Delhi, 110016, India.
Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
Environ Monit Assess. 2017 Aug 10;189(9):445. doi: 10.1007/s10661-017-6146-5.
The presence of 13 polycyclic aromatic hydrocarbons (PAHs) was measured in a small stretch of river Ganges in Kanpur, using high-performance liquid chromatography equipped with photodiode array detector (HPLC/PDA). Non-carcinogenic risk on human health was calculated in the form of hazardous index. Carcinogenic risk was calculated as chronic daily intake and incremental lifetime cancer risk (ILCR) with the help of monitored PAHs in river water. Due to non-availability of reference dose (RfD) values for all the 13 PAHs, the combined hazardous index for three PAHs was calculated. These values in winter, pre-monsoon, and post-monsoon period varied from 6.37 × 10 (Bithoor) to 1.12 × 10 (Jajmau), 2.89 × 10 (Bithoor) to 8.52 × 10 (Annandeshwar Temple), and 1.80 × 10 (Massacre Ghat) to 6.67 × 10 (Jajmau), respectively. In this study, the carcinogenic risk due to PAHs was calculated in the form of ILCR. ILCR due to benzo(a)pyrene (BaP) varied from 1.39 × 10 (Massacre Ghat) to 1.45 × 10 (Jajmau). ILCR was also calculated with the help of BaP for five age groups of people (adults, teenagers, children, toddlers, and infants). The outcome of the study indicates that there is a need to control pollution of the river water to maintain its quality. Continuous discharge of PAHs into the river poses both human health risk and ecological risk.
使用配备光电二极管阵列检测器的高效液相色谱法（HPLC/PDA），对坎普尔恒河的一小段区域中的13种多环芳烃（PAH）进行了测量。以危害指数的形式计算了对人类健康的非致癌风险。借助河水中监测到的PAH，以慢性每日摄入量和终生癌症风险增量（ILCR）的形式计算致癌风险。由于并非所有13种PAH都有参考剂量（RfD）值，因此计算了三种PAH的综合危害指数。这些值在冬季、季风前和季风后时期分别从6.37×10（比图尔）至1.12×10（贾伊毛）、2.89×10（比图尔）至8.52×10（安纳德什瓦尔神庙）以及1.80×10（大屠杀码头）至6.67×10（贾伊毛）不等。在本研究中，以ILCR的形式计算了PAH导致的致癌风险。苯并[a]芘（BaP）导致的ILCR从1.39×10（大屠杀码头）至1.45×10（贾伊毛）不等。还借助BaP为五个年龄组的人群（成年人、青少年、儿童、学步儿童和婴儿）计算了ILCR。研究结果表明，需要控制河水污染以保持其水质。PAH持续排放到河流中会带来人类健康风险和生态风险。
