Cnudde Peter, Nemes Szilard, Mohaddes Maziar, Timperley John, Garellick Göran, Burström Kristina, Rolfson Ola
Swedish Hip Arthroplasty Register, Centre of Registers Västra Götaland, Medicinargatan 18G, SE 413 45 Gothenburg, Sweden.
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, SE 413 45 Gothenburg, Sweden.
Int J Environ Res Public Health. 2017 Aug 10;14(8):899. doi: 10.3390/ijerph14080899.
The influence of comorbidities and worse physical status on mortality following total hip replacement (THR) leads to the idea that patient-reported health status may also be a predictor of mortality. The aim of this study was to investigate the relationship between patient-reported health status before THR and the risk of dying up to 5 years post-operatively. For these analyses, we used register data on 42,862 THR patients with primary hip osteoarthritis operated between 2008 and 2012. The relative survival ratio was calculated by dividing the observed survival in the patient group by age- and sex-adjusted expected survival of the general population. Pre-operative responses to the five EQ-5D-3L (EuroQol Group) dimensions along with age, sex, education status, year of surgery, and hospital type were used as independent variables. Results shown that, as a group, THR patients had a better survival than the general population. Broken down by the five EQ-5D-3L dimensions we observed differentiated survival patters. For all dimensions, those reporting extreme problems had higher mortality than those reporting moderate or no problems. In conclusion, worse health status according to the EQ-5-3L before THR is associated with higher mortality up to five years after surgery. EQ-5D-3L responses may be useful in a multifactorial individualized risk assessment before THR.
合并症和较差身体状况对全髋关节置换术(THR)后死亡率的影响引发了这样一种观点,即患者报告的健康状况也可能是死亡率的一个预测指标。本研究的目的是调查THR术前患者报告的健康状况与术后长达5年的死亡风险之间的关系。对于这些分析,我们使用了2008年至2012年间接受手术的42862例原发性髋骨关节炎THR患者的登记数据。相对生存比率通过将患者组的观察生存率除以按年龄和性别调整后的一般人群预期生存率来计算。术前对五个EQ-5D-3L(欧洲生活质量小组)维度的回答以及年龄、性别、教育状况、手术年份和医院类型用作自变量。结果显示,总体而言,THR患者的生存率高于一般人群。按五个EQ-5D-3L维度细分,我们观察到了不同的生存模式。对于所有维度,报告有极端问题的患者死亡率高于报告有中度问题或无问题的患者。总之,THR术前根据EQ-5-3L评估的较差健康状况与术后长达五年的较高死亡率相关。EQ-5D-3L的回答可能有助于在THR术前进行多因素个体化风险评估。