Department of Dermatology and Allergy, National Allergy Research Centre, Herlev-Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Danish Consumer Council THINK Chemicals, Copenhagen K, Denmark.
J Eur Acad Dermatol Venereol. 2018 Jan;32(1):79-85. doi: 10.1111/jdv.14513. Epub 2017 Sep 11.
More than 25% of the adult European population suffers from contact allergy, with fragrance substances recognized as one of the main causes. Since 2005, 26 fragrance contact allergens have been mandatory to label in cosmetic products within the EU if present at 10 ppm or above in leave-on and 100 ppm or above in wash-off cosmetics.
To examine exposure, based on ingredient labelling, to the 26 fragrances in a sample of 5588 fragranced cosmetic products.
The investigated products were identified through a novel, non-profit smartphone application (app), designed to provide information to consumers about chemical substances in cosmetic products. Products registered through the app between December 2015 and October 2016 were label checked according to International Nomenclature of Cosmetic Ingredients (INCI) for the presence of the 26 fragrance substances or the wording 'fragrance/parfum/aroma'.
The largest product categories investigated were 'cream, lotion and oil' (n = 1192), 'shampoo and conditioner' (n = 968) and 'deodorants' (n = 632). Among cosmetic products labelled to contain at least one of the 26 fragrances, 85.5% and 73.9% contained at least two and at least three of the 26 fragrances, respectively. Linalool (49.5%) and limonene (48.5%) were labelled most often among all investigated products. Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC/Lyral ) was found in 13.5% of deodorants. Six of the 26 fragrance substances were labelled on less than one per cent of all products, including the natural extracts Evernia furfuracea (tree moss) and Evernia prunastri (oak moss). A total of 329 (5.9%) products had one or more of the 26 fragrance substances labelled but did not have 'parfum/fragrance/aroma' listed on the label.
Consumers are widely exposed to, often multiple, well-established fragrance contact allergens through various cosmetic products intended for daily use. Several fragrance substances that are common causes of contact allergy were rarely labelled in this large sample of cosmetic products.
超过 25%的欧洲成年人患有接触性皮炎，而香料物质被认为是主要原因之一。自 2005 年以来，如果在留用型化妆品中存在 10ppm 或以上，或在冲洗型化妆品中存在 100ppm 或以上，欧盟要求在化妆品中必须对 26 种香料接触过敏原进行标签标注。
根据成分标签，检查 5588 种加香化妆品样本中 26 种香料的接触情况。
通过一款新的非盈利智能手机应用程序(app)识别研究产品，该应用程序旨在为消费者提供有关化妆品中化学物质的信息。根据国际化妆品成分命名（INCI），对 2015 年 12 月至 2016 年 10 月期间通过该应用程序注册的产品进行标签检查，以确定 26 种香料物质或“香料/香水/香味”字样的存在。
研究的最大产品类别是“霜、乳液和油”（n=1192）、“洗发水和护发素”（n=968）和“除臭剂”（n=632）。在标签上注明含有至少一种 26 种香料的化妆品中，分别有 85.5%和 73.9%的产品含有至少两种和至少三种 26 种香料。芳樟醇（49.5%）和柠檬烯（48.5%）是所有研究产品中标签标注最频繁的成分。在 13.5%的除臭剂中发现了羟基异己基 3-环己烯甲醛（HICC/Lyral）。在所有产品中，有 6 种 26 种香料物质的标签标注率不到 1%，其中包括天然提取物地衣(Evernia furfuracea，树苔)和地衣(Evernia prunastri，橡苔)。共有 329（5.9%）种产品的标签上标注了一种或多种 26 种香料物质，但标签上未列出“香水/香料/香味”。
消费者通过各种日常使用的化妆品广泛接触到多种已确立的香料接触过敏原，通常是多种过敏原。在这个大型化妆品样本中，很少有标签标注几种常见的接触过敏原香料物质。
