McCrory Cathal, O'Leary Neil, Fraga Silvia, Ribeiro Ana Isabel, Barros Henrique, Kartiosuo Noora, Raitakari Olli, Kivimäki Mika, Vineis Paolo, Layte Richard
The Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland.
Department of EPIUNIT, Institute of Public Health University of Porto, Porto, Portugal.
J Epidemiol Community Health. 2017 Oct;71(10):981-989. doi: 10.1136/jech-2016-208556. Epub 2017 Aug 10.
Height is regarded as a marker of early-life illness, adversity, nutrition and psychosocial stress, but the extent to which differences in height are determined by early-life socioeconomic circumstances, particularly in contemporary populations, is unclear. This study examined socioeconomic differences in children's height trajectories from birth through to 21 years of age in four European countries.
Data were from six prospective cohort studies-Generation XXI, Growing Up in Ireland (infant and child cohorts), Millennium Cohort Study, EPITeen and Cardiovascular Risk in Young Finns Study-comprising a total of 49 492 children with growth measured repeatedly from 1980 to 2014. We modelled differences in children's growth trajectories over time by maternal educational level using hierarchical models with fixed and random components for each cohort study.
Across most cohorts at practically all ages, children from lower educated mothers were shorter on average. The gradient in height was consistently observed at 3 years of age with the difference in expected height between maternal education groups ranging between -0.55 and -1.53 cm for boys and -0.42 to -1.50 cm for girls across the different studies and widening across childhood. The height deficit persists into adolescence and early adulthood. By age 21, boys from primary educated maternal backgrounds lag the tertiary educated by -0.67 cm (Portugal) and -2.15 cm (Finland). The comparable figures for girls were -2.49 cm (Portugal) and -2.93 cm (Finland).
Significant differences in children's height by maternal education persist in modern child populations in Europe.
身高被视为早期疾病、逆境、营养和心理社会压力的一个指标,但身高差异在多大程度上由早期社会经济环境决定,尤其是在当代人群中,尚不清楚。本研究调查了四个欧洲国家儿童从出生到21岁身高轨迹的社会经济差异。
数据来自六项前瞻性队列研究——二十一世纪一代研究、爱尔兰成长研究(婴儿和儿童队列)、千禧队列研究、青少年流行病学研究和芬兰青年人心血管风险研究——总共49492名儿童,他们的生长情况在1980年至2014年期间被反复测量。我们使用每个队列研究的固定和随机成分的分层模型,按母亲教育水平对儿童随时间的生长轨迹差异进行建模。
在几乎所有年龄段的大多数队列中,母亲受教育程度较低的儿童平均身高较矮。在3岁时始终观察到身高梯度,不同研究中母亲教育组之间预期身高的差异,男孩为-0.55至-1.53厘米,女孩为-0.42至-1.50厘米,且在儿童期逐渐扩大。身高差距持续到青春期和成年早期。到21岁时,母亲为小学教育背景的男孩比受过高等教育的男孩矮-0.67厘米(葡萄牙)和-2.15厘米(芬兰)。女孩的相应数字为-2.49厘米(葡萄牙)和-2.93厘米(芬兰)。
在欧洲现代儿童群体中,母亲教育程度不同导致的儿童身高显著差异依然存在。